Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016351604> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2016351604 endingPage "450" @default.
- W2016351604 startingPage "447" @default.
- W2016351604 abstract "The emergence of multidrug-resistant (MDR) strains has made it difficult to treat infections caused by Pseudomonas aeruginosa. In order to develop new alternative therapies for the treatment of MDR P. aeruginosa infections, the antimicrobial activities of different antibiotic combinations have been studied in vitro and in vivo. In this study, the in vitro antimicrobial activities of six different combinations of polymyxins and β-lactams against 34 clinical isolates of P. aeruginosa were evaluated. For the combinations tested by the checkerboard method, an indifferent effect was observed for all strains. However, 27 strains (19 MDR) showed reductions in their minimal inhibitory concentration (MIC) for at least one of the antibiotics in the combinations evaluated. Combination with polymyxins resulted in reductions of the β-lactam MICs, with a change in the resistance category to susceptible in eight MDR strains. These results from the in vitro evaluation suggest that combinations of polymyxins and β-lactams may significantly reduce the MICs of the antibiotics tested. These combinations require further evaluation for use in medical practice." @default.
- W2016351604 created "2016-06-24" @default.
- W2016351604 creator A5019622374 @default.
- W2016351604 creator A5022045770 @default.
- W2016351604 creator A5025001157 @default.
- W2016351604 creator A5033403270 @default.
- W2016351604 creator A5043870710 @default.
- W2016351604 date "2011-11-01" @default.
- W2016351604 modified "2023-10-01" @default.
- W2016351604 title "In vitro activity of polymyxins in combination with β-lactams against clinical strains of Pseudomonas aeruginosa" @default.
- W2016351604 cites W1980325515 @default.
- W2016351604 cites W1982607620 @default.
- W2016351604 cites W2012163448 @default.
- W2016351604 cites W2016562927 @default.
- W2016351604 cites W2023568245 @default.
- W2016351604 cites W2030217583 @default.
- W2016351604 cites W2043209435 @default.
- W2016351604 cites W2052459767 @default.
- W2016351604 cites W2057168149 @default.
- W2016351604 cites W2078978136 @default.
- W2016351604 cites W2096148345 @default.
- W2016351604 cites W2114369028 @default.
- W2016351604 cites W2142188564 @default.
- W2016351604 doi "https://doi.org/10.1016/j.ijantimicag.2011.06.012" @default.
- W2016351604 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21872449" @default.
- W2016351604 hasPublicationYear "2011" @default.
- W2016351604 type Work @default.
- W2016351604 sameAs 2016351604 @default.
- W2016351604 citedByCount "17" @default.
- W2016351604 countsByYear W20163516042013 @default.
- W2016351604 countsByYear W20163516042014 @default.
- W2016351604 countsByYear W20163516042015 @default.
- W2016351604 countsByYear W20163516042016 @default.
- W2016351604 countsByYear W20163516042017 @default.
- W2016351604 countsByYear W20163516042018 @default.
- W2016351604 countsByYear W20163516042019 @default.
- W2016351604 countsByYear W20163516042020 @default.
- W2016351604 countsByYear W20163516042021 @default.
- W2016351604 countsByYear W20163516042023 @default.
- W2016351604 crossrefType "journal-article" @default.
- W2016351604 hasAuthorship W2016351604A5019622374 @default.
- W2016351604 hasAuthorship W2016351604A5022045770 @default.
- W2016351604 hasAuthorship W2016351604A5025001157 @default.
- W2016351604 hasAuthorship W2016351604A5033403270 @default.
- W2016351604 hasAuthorship W2016351604A5043870710 @default.
- W2016351604 hasBestOaLocation W20163516041 @default.
- W2016351604 hasConcept C176947019 @default.
- W2016351604 hasConcept C202751555 @default.
- W2016351604 hasConcept C2777637488 @default.
- W2016351604 hasConcept C2779168147 @default.
- W2016351604 hasConcept C2779259085 @default.
- W2016351604 hasConcept C2780026444 @default.
- W2016351604 hasConcept C2780675486 @default.
- W2016351604 hasConcept C4937899 @default.
- W2016351604 hasConcept C501593827 @default.
- W2016351604 hasConcept C523546767 @default.
- W2016351604 hasConcept C54355233 @default.
- W2016351604 hasConcept C55493867 @default.
- W2016351604 hasConcept C86803240 @default.
- W2016351604 hasConcept C89423630 @default.
- W2016351604 hasConceptScore W2016351604C176947019 @default.
- W2016351604 hasConceptScore W2016351604C202751555 @default.
- W2016351604 hasConceptScore W2016351604C2777637488 @default.
- W2016351604 hasConceptScore W2016351604C2779168147 @default.
- W2016351604 hasConceptScore W2016351604C2779259085 @default.
- W2016351604 hasConceptScore W2016351604C2780026444 @default.
- W2016351604 hasConceptScore W2016351604C2780675486 @default.
- W2016351604 hasConceptScore W2016351604C4937899 @default.
- W2016351604 hasConceptScore W2016351604C501593827 @default.
- W2016351604 hasConceptScore W2016351604C523546767 @default.
- W2016351604 hasConceptScore W2016351604C54355233 @default.
- W2016351604 hasConceptScore W2016351604C55493867 @default.
- W2016351604 hasConceptScore W2016351604C86803240 @default.
- W2016351604 hasConceptScore W2016351604C89423630 @default.
- W2016351604 hasIssue "5" @default.
- W2016351604 hasLocation W20163516041 @default.
- W2016351604 hasLocation W20163516042 @default.
- W2016351604 hasOpenAccess W2016351604 @default.
- W2016351604 hasPrimaryLocation W20163516041 @default.
- W2016351604 hasRelatedWork W1531968212 @default.
- W2016351604 hasRelatedWork W1969134509 @default.
- W2016351604 hasRelatedWork W2016351604 @default.
- W2016351604 hasRelatedWork W2038305694 @default.
- W2016351604 hasRelatedWork W2058911153 @default.
- W2016351604 hasRelatedWork W2337148891 @default.
- W2016351604 hasRelatedWork W2793858051 @default.
- W2016351604 hasRelatedWork W2921332633 @default.
- W2016351604 hasRelatedWork W4229008581 @default.
- W2016351604 hasRelatedWork W4237231762 @default.
- W2016351604 hasVolume "38" @default.
- W2016351604 isParatext "false" @default.
- W2016351604 isRetracted "false" @default.
- W2016351604 magId "2016351604" @default.
- W2016351604 workType "article" @default.