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- W2016353052 abstract "Starvation affects behavior, development, metabolism, reproduction, and longevity in almost all animals including insects. In the American cockroach, Periplaneta americana, we investigated the effect of starvation on organ size and cell proliferation activity of the midgut, over a period of one month, using anti-bromodeoxyuridine (BrdU), and anti-phospho-histone H3 antibodies. Under starvation conditions, the midgut became clear and fragile while its length and diameter were reduced. Both the rate of BrdU-uptake in the nucleus and the mitotic activity shown by anti-phospho-histone H3 antibody decreased under long starvation up to half that of the continuously fed control. Refeeding restored BrdU-uptake and mitosis that overshot the fed control. When casein, starch, or cooking oil was fed as representative nutrient sources to the starved cockroaches, all restored BrdU-uptake, but non-nutrient, talc, did not. This study supports the hypothesis that P. americana has a homeostatic mechanism to regulate the cell population of the midgut epithelium according to changes in the nutritional environment." @default.
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- W2016353052 date "2008-02-01" @default.
- W2016353052 modified "2023-09-25" @default.
- W2016353052 title "Starvation suppresses cell proliferation that rebounds after refeeding in the midgut of the American cockroach, Periplaneta americana" @default.
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- W2016353052 doi "https://doi.org/10.1016/j.jinsphys.2007.10.011" @default.
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