FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016362803> ?p ?o ?g. }

• W2016362803 endingPage "336" @default.
• W2016362803 startingPage "331" @default.
• W2016362803 abstract "Rat parotid responses to sympathetic nerve stimulation in vivo are impaired 2–4 weeks after the induction of streptozotocin diabetes. In this study, the effects of experimental diabetes of similar duration and severity on noradrenaline-stimulated amylase release and cAMP accumulation were examined in vitro. Amylase levels were significantly lower in acinar cells isolated from diabetic animals than in controls, and cellular amylase increased after treatment of the diabetic animals with either thyroxine (T4) or insulin. Diabetes and T4 had no apparent affect on amylase release measured as a percentage of the total. In contrast, giving insulin resulted in a significant reduction in maximal secretion (20.4 ± 2.4% compared with 43.6 ± 7.6%). Similar results were observed when amylase release was stimulated with forskolin. Basal cAMP levels were unaffected by diabetes or T4 (7.8 ± 2.3 pmol/mg protein), but stimulated cAMP levels were significantly greater in diabetic acinar cells than in controls. Insulin reversed the effects of diabetes on cAMP accumulation, whereas T4 had no effect. Thus, diabetes (2–4 weeks) and insulin in vivo appear to have paradoxical effects on parotid amylase release and cAMP accumulation in vitro. Further, the effects of diabetes appear to be unrelated to thyroid status." @default.
• W2016362803 created "2016-06-24" @default.
• W2016362803 creator A5012410236 @default.
• W2016362803 creator A5041572356 @default.
• W2016362803 date "1992-05-01" @default.
• W2016362803 modified "2023-10-17" @default.
• W2016362803 title "Effects of streptozotocin diabetes on amylase release and cAMP accumulation in rat parotid acinar cells" @default.
• W2016362803 cites W104542551 @default.
• W2016362803 cites W1557366298 @default.
• W2016362803 cites W1964246559 @default.
• W2016362803 cites W1964437453 @default.
• W2016362803 cites W1972426610 @default.
• W2016362803 cites W1973511325 @default.
• W2016362803 cites W1985223207 @default.
• W2016362803 cites W1987952841 @default.
• W2016362803 cites W1989526862 @default.
• W2016362803 cites W2009443436 @default.
• W2016362803 cites W2019815441 @default.
• W2016362803 cites W2030278113 @default.
• W2016362803 cites W2033520032 @default.
• W2016362803 cites W2038680180 @default.
• W2016362803 cites W2039730127 @default.
• W2016362803 cites W2042115613 @default.
• W2016362803 cites W2055857435 @default.
• W2016362803 cites W2067977470 @default.
• W2016362803 cites W2071009065 @default.
• W2016362803 cites W2073236248 @default.
• W2016362803 cites W2075297982 @default.
• W2016362803 cites W2075472211 @default.
• W2016362803 cites W2084251994 @default.
• W2016362803 cites W2091712750 @default.
• W2016362803 cites W2111578630 @default.
• W2016362803 cites W2117028974 @default.
• W2016362803 cites W2166792019 @default.
• W2016362803 cites W31359261 @default.
• W2016362803 cites W4232534952 @default.
• W2016362803 cites W4255164024 @default.
• W2016362803 cites W56344301 @default.
• W2016362803 doi "https://doi.org/10.1016/0003-9969(92)90014-y" @default.
• W2016362803 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1376985" @default.
• W2016362803 hasPublicationYear "1992" @default.
• W2016362803 type Work @default.
• W2016362803 sameAs 2016362803 @default.
• W2016362803 citedByCount "12" @default.
• W2016362803 countsByYear W20163628032013 @default.
• W2016362803 countsByYear W20163628032014 @default.
• W2016362803 countsByYear W20163628032015 @default.
• W2016362803 countsByYear W20163628032016 @default.
• W2016362803 crossrefType "journal-article" @default.
• W2016362803 hasAuthorship W2016362803A5012410236 @default.
• W2016362803 hasAuthorship W2016362803A5041572356 @default.
• W2016362803 hasConcept C126322002 @default.
• W2016362803 hasConcept C134018914 @default.
• W2016362803 hasConcept C150903083 @default.
• W2016362803 hasConcept C170835558 @default.
• W2016362803 hasConcept C181199279 @default.
• W2016362803 hasConcept C185592680 @default.
• W2016362803 hasConcept C207001950 @default.
• W2016362803 hasConcept C24998067 @default.
• W2016362803 hasConcept C2778024521 @default.
• W2016362803 hasConcept C2779276759 @default.
• W2016362803 hasConcept C2779280383 @default.
• W2016362803 hasConcept C2779306644 @default.
• W2016362803 hasConcept C55493867 @default.
• W2016362803 hasConcept C555293320 @default.
• W2016362803 hasConcept C71924100 @default.
• W2016362803 hasConcept C86803240 @default.
• W2016362803 hasConceptScore W2016362803C126322002 @default.
• W2016362803 hasConceptScore W2016362803C134018914 @default.
• W2016362803 hasConceptScore W2016362803C150903083 @default.
• W2016362803 hasConceptScore W2016362803C170835558 @default.
• W2016362803 hasConceptScore W2016362803C181199279 @default.
• W2016362803 hasConceptScore W2016362803C185592680 @default.
• W2016362803 hasConceptScore W2016362803C207001950 @default.
• W2016362803 hasConceptScore W2016362803C24998067 @default.
• W2016362803 hasConceptScore W2016362803C2778024521 @default.
• W2016362803 hasConceptScore W2016362803C2779276759 @default.
• W2016362803 hasConceptScore W2016362803C2779280383 @default.
• W2016362803 hasConceptScore W2016362803C2779306644 @default.
• W2016362803 hasConceptScore W2016362803C55493867 @default.
• W2016362803 hasConceptScore W2016362803C555293320 @default.
• W2016362803 hasConceptScore W2016362803C71924100 @default.
• W2016362803 hasConceptScore W2016362803C86803240 @default.
• W2016362803 hasIssue "5" @default.
• W2016362803 hasLocation W20163628031 @default.
• W2016362803 hasLocation W20163628032 @default.
• W2016362803 hasOpenAccess W2016362803 @default.
• W2016362803 hasPrimaryLocation W20163628031 @default.
• W2016362803 hasRelatedWork W1531341651 @default.
• W2016362803 hasRelatedWork W1964961716 @default.
• W2016362803 hasRelatedWork W1985558625 @default.
• W2016362803 hasRelatedWork W2025356055 @default.
• W2016362803 hasRelatedWork W2036681024 @default.
• W2016362803 hasRelatedWork W2044456582 @default.
• W2016362803 hasRelatedWork W2188461759 @default.
• W2016362803 hasRelatedWork W2302924012 @default.
• W2016362803 hasRelatedWork W2420945715 @default.
• W2016362803 hasRelatedWork W2770336673 @default.

• next