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• W2016365848 abstract "1. An epidemiological study of 112 cases of childhood leukemia employing matched sibling and neighborhood control subjects is described. 2. Maternal age at time of birth of the leukemia patients was, on the average, more than two years greater than maternal age at the time of birth of the neighborhood control children. The excess in maternal age is equally apparent even when the mothers of the leukemia patients with mongolism are excluded. 3. Birth order averaged 0.46 births later in leukemia patients than in neighborhood control children. However, the leukemia case series contained an excess of children of lower birth order than the Minnesota population of live births in the corresponding years. 4. Mongolism was encountered in eight of the studied leukemia cases (nine of the available cases), in no sibling control subjects and in one neighborhood control subject. The frequency of association of leukemia and mongolism in this series is significantly greater than has been reported previously. 5. A verified history of antenatal X-ray exposure was shown to be somewhat more common among the leukemia patients aged 0–4 years than in either control group. This difference was not statistically significant. 6. A verified history of X-ray exposure up to one year before death was shown to be somewhat more common in the leukemia patients aged 0–4 years than in the matched control children. This difference was not statistically significant. 7. Histories of allergies and common communicable diseases were too infrequent to permit analyses of possible disparities in attack rates of these diseases between the leukemia patients and control groups. 8. Data collected on chemical exposures and usage of drugs were not considered sufficiently reliable to warrant detailed analysis. Such information was very difficult to verify, and is thought to reflect considerable parental bias." @default.
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• W2016365848 date "1965-02-01" @default.
• W2016365848 modified "2023-10-09" @default.
• W2016365848 title "An epidemiological study of childhood leukemia" @default.
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• W2016365848 doi "https://doi.org/10.1016/0021-9681(65)90096-2" @default.
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