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• W2016380822 abstract "Signal transducer and activation of transcription (STAT)6 has a central role in the signal transduction of interleukin (IL)-4 and IL-13. It has recently been revealed that STAT3 is also involved. STAT6 and STAT3 are expressed ubiquitously; however, it remains unknown how STAT6 and STAT3 expression is regulated. In this study, we found that STAT6 expression was augmented at the transcription level in B and T cells stimulated with anti-IgM antibody and anti-CD40 antibody or PMA and ionomycin, respectively, and that STAT3 expression was similarly augmented in the stimulated B cells. The stimulated B and T cells showed enhancement of STAT6 activation and CD23 expression induced by IL-4 and IL-13. Augmentation of STAT6 and STAT3 would be a mechanism of the amplification of the IL-4 and IL-13 signals in stimulated B and T cells." @default.
• W2016380822 created "2016-06-24" @default.
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• W2016380822 date "2000-10-01" @default.
• W2016380822 modified "2023-10-06" @default.
• W2016380822 title "Augmentation of Signal Transducer and Activation of Transcription (STAT)6 and STAT3 Expression in Stimulated B and T Cells" @default.
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• W2016380822 doi "https://doi.org/10.1006/bbrc.2000.3674" @default.
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