FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016394900> ?p ?o ?g. }

• W2016394900 endingPage "441" @default.
• W2016394900 startingPage "437" @default.
• W2016394900 abstract "The mammalian target of rapamycin (mTOR) controls cell growth in response to amino acids and growth factors, in part by regulating p70 S6 kinase alpha (p70 alpha) and eukaryotic initiation factor 4E binding protein 1 (4EBP1). Raptor (regulatory associated protein of mTOR) is a 150 kDa mTOR binding protein that is essential for TOR signaling in vivo and also binds 4EBP1 and p70alpha through their respective TOS (TOR signaling) motifs, a short conserved segment previously shown to be required for amino acid- and mTOR-dependent regulation of these substrates in vivo. Raptor appears to serve as an mTOR scaffold protein, the binding of which to the TOS motif of mTOR substrates is necessary for effective mTOR-catalyzed phosphorylation. Further understanding of regulation of the mTOR-raptor complex in response to the nutritional environment would require identification of the interplay between the mTOR-raptor complex and its upstream effectors such as the protein products of tumor suppressor gene tuberous sclerosis complexes 1 and 2, and the Ras-related small G protein Rheb." @default.
• W2016394900 created "2016-06-24" @default.
• W2016394900 creator A5029163724 @default.
• W2016394900 creator A5070235885 @default.
• W2016394900 creator A5071170327 @default.
• W2016394900 creator A5078677779 @default.
• W2016394900 date "2004-01-01" @default.
• W2016394900 modified "2023-10-16" @default.
• W2016394900 title "Raptor, a binding partner of target of rapamycin" @default.
• W2016394900 cites W1529848395 @default.
• W2016394900 cites W1979612739 @default.
• W2016394900 cites W1979819215 @default.
• W2016394900 cites W1985046929 @default.
• W2016394900 cites W1987105275 @default.
• W2016394900 cites W1992480202 @default.
• W2016394900 cites W1998762942 @default.
• W2016394900 cites W1999056466 @default.
• W2016394900 cites W2002031023 @default.
• W2016394900 cites W2006559495 @default.
• W2016394900 cites W2008239768 @default.
• W2016394900 cites W2012142261 @default.
• W2016394900 cites W2035016947 @default.
• W2016394900 cites W2036254130 @default.
• W2016394900 cites W2044301435 @default.
• W2016394900 cites W2048059265 @default.
• W2016394900 cites W2055248589 @default.
• W2016394900 cites W2062801148 @default.
• W2016394900 cites W2067765926 @default.
• W2016394900 cites W2069969811 @default.
• W2016394900 cites W2076024460 @default.
• W2016394900 cites W2087136249 @default.
• W2016394900 cites W2090407808 @default.
• W2016394900 cites W2093916539 @default.
• W2016394900 cites W2099389441 @default.
• W2016394900 cites W2108478376 @default.
• W2016394900 cites W2119194577 @default.
• W2016394900 cites W2139856846 @default.
• W2016394900 cites W2144059623 @default.
• W2016394900 cites W2152600551 @default.
• W2016394900 cites W2157992174 @default.
• W2016394900 cites W2336586723 @default.
• W2016394900 doi "https://doi.org/10.1016/j.bbrc.2003.07.018" @default.
• W2016394900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14684181" @default.
• W2016394900 hasPublicationYear "2004" @default.
• W2016394900 type Work @default.
• W2016394900 sameAs 2016394900 @default.
• W2016394900 citedByCount "83" @default.
• W2016394900 countsByYear W20163949002012 @default.
• W2016394900 countsByYear W20163949002013 @default.
• W2016394900 countsByYear W20163949002014 @default.
• W2016394900 countsByYear W20163949002015 @default.
• W2016394900 countsByYear W20163949002016 @default.
• W2016394900 countsByYear W20163949002018 @default.
• W2016394900 countsByYear W20163949002019 @default.
• W2016394900 countsByYear W20163949002020 @default.
• W2016394900 countsByYear W20163949002021 @default.
• W2016394900 countsByYear W20163949002022 @default.
• W2016394900 countsByYear W20163949002023 @default.
• W2016394900 crossrefType "journal-article" @default.
• W2016394900 hasAuthorship W2016394900A5029163724 @default.
• W2016394900 hasAuthorship W2016394900A5070235885 @default.
• W2016394900 hasAuthorship W2016394900A5071170327 @default.
• W2016394900 hasAuthorship W2016394900A5078677779 @default.
• W2016394900 hasConcept C104202773 @default.
• W2016394900 hasConcept C107846503 @default.
• W2016394900 hasConcept C11960822 @default.
• W2016394900 hasConcept C2777949483 @default.
• W2016394900 hasConcept C2778937405 @default.
• W2016394900 hasConcept C2909523446 @default.
• W2016394900 hasConcept C43060935 @default.
• W2016394900 hasConcept C51785407 @default.
• W2016394900 hasConcept C62478195 @default.
• W2016394900 hasConcept C86554907 @default.
• W2016394900 hasConcept C86803240 @default.
• W2016394900 hasConcept C95444343 @default.
• W2016394900 hasConcept C98490376 @default.
• W2016394900 hasConceptScore W2016394900C104202773 @default.
• W2016394900 hasConceptScore W2016394900C107846503 @default.
• W2016394900 hasConceptScore W2016394900C11960822 @default.
• W2016394900 hasConceptScore W2016394900C2777949483 @default.
• W2016394900 hasConceptScore W2016394900C2778937405 @default.
• W2016394900 hasConceptScore W2016394900C2909523446 @default.
• W2016394900 hasConceptScore W2016394900C43060935 @default.
• W2016394900 hasConceptScore W2016394900C51785407 @default.
• W2016394900 hasConceptScore W2016394900C62478195 @default.
• W2016394900 hasConceptScore W2016394900C86554907 @default.
• W2016394900 hasConceptScore W2016394900C86803240 @default.
• W2016394900 hasConceptScore W2016394900C95444343 @default.
• W2016394900 hasConceptScore W2016394900C98490376 @default.
• W2016394900 hasIssue "2" @default.
• W2016394900 hasLocation W20163949001 @default.
• W2016394900 hasLocation W20163949002 @default.
• W2016394900 hasOpenAccess W2016394900 @default.
• W2016394900 hasPrimaryLocation W20163949001 @default.
• W2016394900 hasRelatedWork W1487550568 @default.
• W2016394900 hasRelatedWork W1971357899 @default.
• W2016394900 hasRelatedWork W1990637185 @default.
• W2016394900 hasRelatedWork W1994186909 @default.

• next