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- W2016405445 abstract "The presence of PH in patients who suffer from CHF is common and predicts a poor outcome. However, precise definitions for PH associated with left heart disease, or 'out-of-proportion' PH as well as standardised vasodilator testing protocols are lacking. Moreover, apart from single-centre observations no large-scale trial to date has demonstrated a long-term benefit from pulmonary vasoactive drugs. As a result, there are currently no consensus recommendations for the treatment of PH in the presence of CHF. Off-label use of specific vasodilators in this patient population is discouraged. In a majority of cases, treatment of the underlying left heart disease leads to a decrease in pulmonary pressures. In light of novel agents to treat PH, trials that specifically address 'out-of-proportion' PH in CHF patients are warranted." @default.
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- W2016405445 date "2009-03-01" @default.
- W2016405445 modified "2023-09-26" @default.
- W2016405445 title "Pulmonary hypertension in chronic heart failure" @default.
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- W2016405445 doi "https://doi.org/10.1111/j.1742-1241.2008.01950.x" @default.
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