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- W2016408461 abstract "We have recently identified the HMG box transcription factor Sox-13 and described its expression during murine embryogenesis. Here we describe the structure of the murineSox-13gene. This gene spans approximately 12 kb and consists of 13 exons. The HMG domain is encoded by exons XI and XII, separated by an intron that is conserved amongSox-5, Sox-13,andSox-17.A single major transcription initiation site was identified. Deletion analysis of the 3-kb promoter region revealed a 400-bp fragment driving transcription of a luciferase reporter in aSox-13-expressing cell line. To determine the chromosomal localization of the human gene, a humanSOX13cDNA was isolated with 75% homology to the mouseSox-13.FISH analysis mapped the humanSOX13gene to chromosome 1 band q32." @default.
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- W2016408461 date "1999-04-01" @default.
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- W2016408461 title "TheSox-13Gene: Structure, Promoter Characterization, and Chromosomal Localization" @default.
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- W2016408461 doi "https://doi.org/10.1006/geno.1999.5779" @default.
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