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- W2016429360 abstract "Regulatory T cells (Tregs) that expand in human colon cancer express retinoid-related orphan receptor γt (RORγt) and exert potent T-cell suppressive functions while mediating pro-inflammatory effects. Similar Tregs expand and drive a vicious cycle of inflammation in murine polyposis. Targeting RORγt in Tregs interrupts such a cycle and protects mice against polyposis, suggesting that a similar intervention may provide therapeutic benefits to colon cancer patients." @default.
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- W2016429360 date "2013-05-01" @default.
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- W2016429360 title "The two faces of regulatory T cells in cancer" @default.
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- W2016429360 doi "https://doi.org/10.4161/onci.23852" @default.
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