FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016455246> ?p ?o ?g. }

• W2016455246 endingPage "705" @default.
• W2016455246 startingPage "698" @default.
• W2016455246 abstract "Advanced maternal age and altered recombination are known risk factors for Down syndrome cases due to maternal nondisjunction of chromosome 21, whereas the impact of other environmental and genetic factors is unclear. The aim of this study was to investigate an association between low maternal socioeconomic status and chromosome 21 nondisjunction.Data from 714 case and 977 control families were used to assess chromosome 21 meiosis I and meiosis II nondisjunction errors in the presence of three low socioeconomic status factors: (i) both parents had not completed high school, (ii) both maternal grandparents had not completed high school, and (iii) an annual household income of <$25,000. We applied logistic regression models and adjusted for covariates, including maternal age and race/ethnicity.As compared with mothers of controls (n = 977), mothers with meiosis II chromosome 21 nondisjunction (n = 182) were more likely to have a history of one low socioeconomic status factor (odds ratio = 1.81; 95% confidence interval = 1.07-3.05) and ≥2 low socioeconomic status factors (odds ratio = 2.17; 95% confidence interval = 1.02-4.63). This association was driven primarily by having a low household income (odds ratio = 1.79; 95% confidence interval = 1.14-2.73). The same statistically significant association was not detected among maternal meiosis I errors (odds ratio = 1.31; 95% confidence interval = 0.81-2.10), in spite of having a larger sample size (n = 532).We detected a significant association between low maternal socioeconomic status and meiosis II chromosome 21 nondisjunction. Further studies are warranted to explore which aspects of low maternal socioeconomic status, such as environmental exposures or poor nutrition, may account for these results." @default.
• W2016455246 created "2016-06-24" @default.
• W2016455246 creator A5005523815 @default.
• W2016455246 creator A5010485441 @default.
• W2016455246 creator A5014880493 @default.
• W2016455246 creator A5022738034 @default.
• W2016455246 creator A5046083954 @default.
• W2016455246 creator A5049260570 @default.
• W2016455246 creator A5049663022 @default.
• W2016455246 creator A5051901335 @default.
• W2016455246 creator A5058117644 @default.
• W2016455246 creator A5060779836 @default.
• W2016455246 creator A5071814533 @default.
• W2016455246 creator A5074486406 @default.
• W2016455246 creator A5080785848 @default.
• W2016455246 date "2013-09-01" @default.
• W2016455246 modified "2023-10-14" @default.
• W2016455246 title "The association of low socioeconomic status and the risk of having a child with Down syndrome: a report from the National Down Syndrome Project" @default.
• W2016455246 cites W1525231237 @default.
• W2016455246 cites W1584137435 @default.
• W2016455246 cites W1963754762 @default.
• W2016455246 cites W1978515381 @default.
• W2016455246 cites W1987571337 @default.
• W2016455246 cites W1996765504 @default.
• W2016455246 cites W1997265333 @default.
• W2016455246 cites W1997559493 @default.
• W2016455246 cites W2005238839 @default.
• W2016455246 cites W2017293813 @default.
• W2016455246 cites W2021647091 @default.
• W2016455246 cites W2021722496 @default.
• W2016455246 cites W2022793225 @default.
• W2016455246 cites W2024978198 @default.
• W2016455246 cites W2031847595 @default.
• W2016455246 cites W2041002646 @default.
• W2016455246 cites W2042334757 @default.
• W2016455246 cites W2054831080 @default.
• W2016455246 cites W2066594097 @default.
• W2016455246 cites W2068493953 @default.
• W2016455246 cites W2070048674 @default.
• W2016455246 cites W2074682455 @default.
• W2016455246 cites W2075520328 @default.
• W2016455246 cites W2075815267 @default.
• W2016455246 cites W2087269413 @default.
• W2016455246 cites W2090589400 @default.
• W2016455246 cites W2091539196 @default.
• W2016455246 cites W2094746916 @default.
• W2016455246 cites W2094883525 @default.
• W2016455246 cites W2102357487 @default.
• W2016455246 cites W2111498062 @default.
• W2016455246 cites W2128972377 @default.
• W2016455246 cites W2129061276 @default.
• W2016455246 cites W2155866830 @default.
• W2016455246 cites W2157077875 @default.
• W2016455246 cites W2157338534 @default.
• W2016455246 cites W2186770490 @default.
• W2016455246 cites W2410260699 @default.
• W2016455246 doi "https://doi.org/10.1038/gim.2013.34" @default.
• W2016455246 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4122862" @default.
• W2016455246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23558253" @default.
• W2016455246 hasPublicationYear "2013" @default.
• W2016455246 type Work @default.
• W2016455246 sameAs 2016455246 @default.
• W2016455246 citedByCount "28" @default.
• W2016455246 countsByYear W20164552462013 @default.
• W2016455246 countsByYear W20164552462015 @default.
• W2016455246 countsByYear W20164552462016 @default.
• W2016455246 countsByYear W20164552462017 @default.
• W2016455246 countsByYear W20164552462018 @default.
• W2016455246 countsByYear W20164552462019 @default.
• W2016455246 countsByYear W20164552462020 @default.
• W2016455246 countsByYear W20164552462021 @default.
• W2016455246 countsByYear W20164552462022 @default.
• W2016455246 countsByYear W20164552462023 @default.
• W2016455246 crossrefType "journal-article" @default.
• W2016455246 hasAuthorship W2016455246A5005523815 @default.
• W2016455246 hasAuthorship W2016455246A5010485441 @default.
• W2016455246 hasAuthorship W2016455246A5014880493 @default.
• W2016455246 hasAuthorship W2016455246A5022738034 @default.
• W2016455246 hasAuthorship W2016455246A5046083954 @default.
• W2016455246 hasAuthorship W2016455246A5049260570 @default.
• W2016455246 hasAuthorship W2016455246A5049663022 @default.
• W2016455246 hasAuthorship W2016455246A5051901335 @default.
• W2016455246 hasAuthorship W2016455246A5058117644 @default.
• W2016455246 hasAuthorship W2016455246A5060779836 @default.
• W2016455246 hasAuthorship W2016455246A5071814533 @default.
• W2016455246 hasAuthorship W2016455246A5074486406 @default.
• W2016455246 hasAuthorship W2016455246A5080785848 @default.
• W2016455246 hasBestOaLocation W20164552461 @default.
• W2016455246 hasConcept C104317684 @default.
• W2016455246 hasConcept C126322002 @default.
• W2016455246 hasConcept C144024400 @default.
• W2016455246 hasConcept C147077947 @default.
• W2016455246 hasConcept C149923435 @default.
• W2016455246 hasConcept C156957248 @default.
• W2016455246 hasConcept C2779066155 @default.
• W2016455246 hasConcept C2779672484 @default.
• W2016455246 hasConcept C2779954681 @default.
• W2016455246 hasConcept C2908647359 @default.

• next