Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016456073> ?p ?o ?g. }
- W2016456073 endingPage "1428" @default.
- W2016456073 startingPage "1415" @default.
- W2016456073 abstract "Endocrine therapy is a major treatment modality for hormone-dependent breast cancer. It has a relatively low morbidity, and there is evidence that antihormonal treatments have had a significant effect in reducing mortality for breast cancer. Despite this, resistance to endocrine therapy, either primary or acquired during treatment, occurs in the majority of patients, and is a major obstacle to optimal clinical management. There is therefore an urgent need to identify, on an individual basis, those tumors that are most likely to respond to endocrine therapy (so sparing patients with resistant tumors the needless side effects of ineffective therapy), and the mechanisms of resistance in tumors that are nonresponsive to treatment (so these can be bypassed). These needs are the focus of this review, which discusses the particular issues encountered when investigating the potential of multigene expression signatures as predictive factors for response to aromatase inhibitors, which have recently become front-line endocrine therapies for postmenopausal patients with breast cancer." @default.
- W2016456073 created "2016-06-24" @default.
- W2016456073 creator A5022540272 @default.
- W2016456073 creator A5084311056 @default.
- W2016456073 date "2009-11-01" @default.
- W2016456073 modified "2023-09-27" @default.
- W2016456073 title "Challenges in defining predictive markers for response to endocrine therapy in breast cancer" @default.
- W2016456073 cites W1271389891 @default.
- W2016456073 cites W1488006870 @default.
- W2016456073 cites W1541462539 @default.
- W2016456073 cites W1542816299 @default.
- W2016456073 cites W1575982426 @default.
- W2016456073 cites W1600272042 @default.
- W2016456073 cites W1608577156 @default.
- W2016456073 cites W1677902772 @default.
- W2016456073 cites W1694119819 @default.
- W2016456073 cites W1696199194 @default.
- W2016456073 cites W1969362786 @default.
- W2016456073 cites W1977221327 @default.
- W2016456073 cites W1981509058 @default.
- W2016456073 cites W1988319444 @default.
- W2016456073 cites W1995056702 @default.
- W2016456073 cites W2001116848 @default.
- W2016456073 cites W2002193090 @default.
- W2016456073 cites W2007461054 @default.
- W2016456073 cites W2007700157 @default.
- W2016456073 cites W2010637767 @default.
- W2016456073 cites W2013956549 @default.
- W2016456073 cites W2018608564 @default.
- W2016456073 cites W2021129827 @default.
- W2016456073 cites W2022797399 @default.
- W2016456073 cites W2025914878 @default.
- W2016456073 cites W2043235003 @default.
- W2016456073 cites W2047518704 @default.
- W2016456073 cites W2052383391 @default.
- W2016456073 cites W2053892726 @default.
- W2016456073 cites W2055815141 @default.
- W2016456073 cites W2062536451 @default.
- W2016456073 cites W2066027217 @default.
- W2016456073 cites W2070313422 @default.
- W2016456073 cites W2071370738 @default.
- W2016456073 cites W2081580289 @default.
- W2016456073 cites W2082364878 @default.
- W2016456073 cites W2086891750 @default.
- W2016456073 cites W2089615291 @default.
- W2016456073 cites W2094984378 @default.
- W2016456073 cites W2096620495 @default.
- W2016456073 cites W2101224880 @default.
- W2016456073 cites W2105981176 @default.
- W2016456073 cites W2106026658 @default.
- W2016456073 cites W2109034705 @default.
- W2016456073 cites W2114167623 @default.
- W2016456073 cites W2116126879 @default.
- W2016456073 cites W2116302563 @default.
- W2016456073 cites W2117251248 @default.
- W2016456073 cites W2118782378 @default.
- W2016456073 cites W2119126673 @default.
- W2016456073 cites W2120991664 @default.
- W2016456073 cites W2123945948 @default.
- W2016456073 cites W2127362596 @default.
- W2016456073 cites W2129172482 @default.
- W2016456073 cites W2132135065 @default.
- W2016456073 cites W2133764807 @default.
- W2016456073 cites W2134444110 @default.
- W2016456073 cites W2138740534 @default.
- W2016456073 cites W2140864052 @default.
- W2016456073 cites W2143185770 @default.
- W2016456073 cites W2148063507 @default.
- W2016456073 cites W2148796794 @default.
- W2016456073 cites W2154195517 @default.
- W2016456073 cites W2156273110 @default.
- W2016456073 cites W2159607078 @default.
- W2016456073 cites W2161183734 @default.
- W2016456073 cites W2164095252 @default.
- W2016456073 cites W2165241692 @default.
- W2016456073 cites W2165432902 @default.
- W2016456073 cites W2168619066 @default.
- W2016456073 cites W2169002484 @default.
- W2016456073 cites W2196919854 @default.
- W2016456073 cites W2303537833 @default.
- W2016456073 cites W2590195772 @default.
- W2016456073 cites W28038445 @default.
- W2016456073 cites W3162684029 @default.
- W2016456073 cites W4248288803 @default.
- W2016456073 cites W115263797 @default.
- W2016456073 doi "https://doi.org/10.2217/fon.09.113" @default.
- W2016456073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19903069" @default.
- W2016456073 hasPublicationYear "2009" @default.
- W2016456073 type Work @default.
- W2016456073 sameAs 2016456073 @default.
- W2016456073 citedByCount "23" @default.
- W2016456073 countsByYear W20164560732014 @default.
- W2016456073 countsByYear W20164560732015 @default.
- W2016456073 countsByYear W20164560732016 @default.
- W2016456073 countsByYear W20164560732018 @default.
- W2016456073 countsByYear W20164560732019 @default.
- W2016456073 countsByYear W20164560732022 @default.
- W2016456073 crossrefType "journal-article" @default.