FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016459158> ?p ?o ?g. }

• W2016459158 endingPage "1117" @default.
• W2016459158 startingPage "1097" @default.
• W2016459158 abstract "For the treatment of localised renal cell carcinoma (RCC), uncertainties remain over the perioperative and quality-of-life (QoL) outcomes for the many different surgical techniques and approaches of nephrectomy. Controversy also remains on whether newer minimally invasive nephron-sparing interventions offer better QoL and perioperative outcomes, and whether adrenalectomy and lymphadenectomy should be performed simultaneously with nephrectomy. These non-oncological outcomes are important because they may have a considerable impact on localised RCC treatment decision making.To review systematically all the relevant published literature comparing perioperative and QoL outcomes of surgical management of localised RCC (T1-2N0M0).Relevant databases including Medline, Embase, and the Cochrane Library were searched up to January 2012. Randomised controlled trials (RCTs) or quasi-randomised controlled trials, prospective observational studies with controls, retrospective matched-pair studies, and comparative studies from well-defined registries/databases were included. The outcome measures were QoL, analgesic requirement, length of hospital stay, time to normal activity level, surgical morbidity and complications, ischaemia time, renal function, blood loss, length of operation, need for blood transfusion, and perioperative mortality. The Cochrane risk of bias tool was used to assess RCTs, and an extended version was used to assess nonrandomised studies (NRSs). The quality of evidence was assessed using Grading of Recommendations, Assessment, Development, and Evaluation.A total of 4580 abstracts and 380 full-text articles were assessed, and 29 studies met the inclusion criteria (7 RCTs and 22 NRSs). There were high risks of bias and low-quality evidence for studies meeting the inclusion criteria. There is good evidence indicating that partial nephrectomy results in better preservation of renal function and better QoL outcomes than radical nephrectomy regardless of technique or approach. Regarding radical nephrectomy, the laparoscopic approach has better perioperative outcomes than the open approach, and there is no evidence of a difference between the transperitoneal and retroperitoneal approaches. Alternatives to standard laparoscopic radical nephrectomy (LRN) such as hand-assisted, robot-assisted, or single-port techniques appear to have similar perioperative outcomes. There is no good evidence to suggest that minimally invasive procedures such as cryotherapy or radiofrequency ablation have superior perioperative or QoL outcomes to nephrectomy. Regarding concomitant lymphadenectomy during nephrectomy, there were low event rates for complications, and no definitive difference was observed. There was no evidence to base statements about concomitant ipsilateral adrenalectomy during nephrectomy.Partial nephrectomy results in significantly better preservation of renal function over radical nephrectomy. For tumours where partial nephrectomy is not technically feasible, there is no evidence that alternative procedures or techniques are better than LRN in terms of perioperative or QoL outcomes. In making treatment decisions, perioperative and QoL outcomes should be considered in conjunction with oncological outcomes. Overall, there was a paucity of data regarding QoL outcomes, and when reported, both QoL and perioperative outcomes were inconsistently defined, measured, or reported. The current evidence base has major limitations due to studies of low methodological quality marked by high risks of bias." @default.
• W2016459158 created "2016-06-24" @default.
• W2016459158 creator A5001861927 @default.
• W2016459158 creator A5002370307 @default.
• W2016459158 creator A5004165162 @default.
• W2016459158 creator A5013203178 @default.
• W2016459158 creator A5017033561 @default.
• W2016459158 creator A5018595176 @default.
• W2016459158 creator A5018724250 @default.
• W2016459158 creator A5029542738 @default.
• W2016459158 creator A5052809243 @default.
• W2016459158 creator A5058932170 @default.
• W2016459158 creator A5062834106 @default.
• W2016459158 creator A5067772235 @default.
• W2016459158 creator A5069321364 @default.
• W2016459158 creator A5077678731 @default.
• W2016459158 creator A5080375827 @default.
• W2016459158 creator A5085935947 @default.
• W2016459158 date "2012-12-01" @default.
• W2016459158 modified "2023-10-04" @default.
• W2016459158 title "Systematic Review of Perioperative and Quality-of-life Outcomes Following Surgical Management of Localised Renal Cancer" @default.
• W2016459158 cites W1551137472 @default.
• W2016459158 cites W1561426946 @default.
• W2016459158 cites W1795855832 @default.
• W2016459158 cites W1968559054 @default.
• W2016459158 cites W1976576973 @default.
• W2016459158 cites W1978038500 @default.
• W2016459158 cites W1979366344 @default.
• W2016459158 cites W1981031360 @default.
• W2016459158 cites W1981972946 @default.
• W2016459158 cites W1983250560 @default.
• W2016459158 cites W1983746588 @default.
• W2016459158 cites W1991406747 @default.
• W2016459158 cites W1994604939 @default.
• W2016459158 cites W1994937208 @default.
• W2016459158 cites W1997039476 @default.
• W2016459158 cites W1998340707 @default.
• W2016459158 cites W1999220961 @default.
• W2016459158 cites W2000587976 @default.
• W2016459158 cites W2006150388 @default.
• W2016459158 cites W2021719308 @default.
• W2016459158 cites W2031703734 @default.
• W2016459158 cites W2035459304 @default.
• W2016459158 cites W2039948400 @default.
• W2016459158 cites W2045635808 @default.
• W2016459158 cites W2051958276 @default.
• W2016459158 cites W2059075213 @default.
• W2016459158 cites W2074517129 @default.
• W2016459158 cites W2079432903 @default.
• W2016459158 cites W2080600221 @default.
• W2016459158 cites W2087254177 @default.
• W2016459158 cites W2087813694 @default.
• W2016459158 cites W2088618615 @default.
• W2016459158 cites W2092298515 @default.
• W2016459158 cites W2102057116 @default.
• W2016459158 cites W2102072344 @default.
• W2016459158 cites W2106602966 @default.
• W2016459158 cites W2109431784 @default.
• W2016459158 cites W2121919182 @default.
• W2016459158 cites W2123344349 @default.
• W2016459158 cites W2125435699 @default.
• W2016459158 cites W2126228817 @default.
• W2016459158 cites W2130020900 @default.
• W2016459158 cites W2139030344 @default.
• W2016459158 cites W2139955933 @default.
• W2016459158 cites W2155255836 @default.
• W2016459158 cites W2156636993 @default.
• W2016459158 cites W2159930420 @default.
• W2016459158 cites W2165036089 @default.
• W2016459158 cites W2167545922 @default.
• W2016459158 cites W2793509215 @default.
• W2016459158 cites W2911611736 @default.
• W2016459158 cites W4292806894 @default.
• W2016459158 doi "https://doi.org/10.1016/j.eururo.2012.07.028" @default.
• W2016459158 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22841673" @default.
• W2016459158 hasPublicationYear "2012" @default.
• W2016459158 type Work @default.
• W2016459158 sameAs 2016459158 @default.
• W2016459158 citedByCount "205" @default.
• W2016459158 countsByYear W20164591582013 @default.
• W2016459158 countsByYear W20164591582014 @default.
• W2016459158 countsByYear W20164591582015 @default.
• W2016459158 countsByYear W20164591582016 @default.
• W2016459158 countsByYear W20164591582017 @default.
• W2016459158 countsByYear W20164591582018 @default.
• W2016459158 countsByYear W20164591582019 @default.
• W2016459158 countsByYear W20164591582020 @default.
• W2016459158 countsByYear W20164591582021 @default.
• W2016459158 countsByYear W20164591582022 @default.
• W2016459158 countsByYear W20164591582023 @default.
• W2016459158 crossrefType "journal-article" @default.
• W2016459158 hasAuthorship W2016459158A5001861927 @default.
• W2016459158 hasAuthorship W2016459158A5002370307 @default.
• W2016459158 hasAuthorship W2016459158A5004165162 @default.
• W2016459158 hasAuthorship W2016459158A5013203178 @default.
• W2016459158 hasAuthorship W2016459158A5017033561 @default.
• W2016459158 hasAuthorship W2016459158A5018595176 @default.
• W2016459158 hasAuthorship W2016459158A5018724250 @default.

• next