FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016472144> ?p ?o ?g. }

• W2016472144 endingPage "e52438" @default.
• W2016472144 startingPage "e52438" @default.
• W2016472144 abstract "Variability in blood pressure predicts cardiovascular disease in young- and middle-aged subjects, but relevant data for older individuals are sparse. We analysed data from the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) study of 5804 participants aged 70–82 years with a history of, or risk factors for cardiovascular disease. Visit-to-visit variability in blood pressure (standard deviation) was determined using a minimum of five measurements over 1 year; an inception cohort of 4819 subjects had subsequent in-trial 3 years follow-up; longer-term follow-up (mean 7.1 years) was available for 1808 subjects. Higher systolic blood pressure variability independently predicted long-term follow-up vascular and total mortality (hazard ratio per 5 mmHg increase in standard deviation of systolic blood pressure = 1.2, 95% confidence interval 1.1–1.4; hazard ratio 1.1, 95% confidence interval 1.1–1.2, respectively). Variability in diastolic blood pressure associated with increased risk for coronary events (hazard ratio 1.5, 95% confidence interval 1.2–1.8 for each 5 mmHg increase), heart failure hospitalisation (hazard ratio 1.4, 95% confidence interval 1.1–1.8) and vascular (hazard ratio 1.4, 95% confidence interval 1.1–1.7) and total mortality (hazard ratio 1.3, 95% confidence interval 1.1–1.5), all in long-term follow-up. Pulse pressure variability was associated with increased stroke risk (hazard ratio 1.2, 95% confidence interval 1.0–1.4 for each 5 mmHg increase), vascular mortality (hazard ratio 1.2, 95% confidence interval 1.0–1.3) and total mortality (hazard ratio 1.1, 95% confidence interval 1.0–1.2), all in long-term follow-up. All associations were independent of respective mean blood pressure levels, age, gender, in-trial treatment group (pravastatin or placebo) and prior vascular disease and cardiovascular disease risk factors. Our observations suggest variability in diastolic blood pressure is more strongly associated with vascular or total mortality than is systolic pressure variability in older high-risk subjects." @default.
• W2016472144 created "2016-06-24" @default.
• W2016472144 creator A5000002986 @default.
• W2016472144 creator A5005451442 @default.
• W2016472144 creator A5005535605 @default.
• W2016472144 creator A5013373829 @default.
• W2016472144 creator A5016095791 @default.
• W2016472144 creator A5017836069 @default.
• W2016472144 creator A5023142491 @default.
• W2016472144 creator A5031245545 @default.
• W2016472144 creator A5036896719 @default.
• W2016472144 creator A5037853560 @default.
• W2016472144 creator A5078498803 @default.
• W2016472144 creator A5091160797 @default.
• W2016472144 date "2012-12-20" @default.
• W2016472144 modified "2023-10-18" @default.
• W2016472144 title "Blood Pressure Variability and Cardiovascular Risk in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER)" @default.
• W2016472144 cites W1976848870 @default.
• W2016472144 cites W1981141177 @default.
• W2016472144 cites W2015124409 @default.
• W2016472144 cites W2025309234 @default.
• W2016472144 cites W2025362250 @default.
• W2016472144 cites W2030259518 @default.
• W2016472144 cites W2030557186 @default.
• W2016472144 cites W2044451379 @default.
• W2016472144 cites W2053472585 @default.
• W2016472144 cites W2094418975 @default.
• W2016472144 cites W2097364117 @default.
• W2016472144 cites W2104192390 @default.
• W2016472144 cites W2108651298 @default.
• W2016472144 cites W2111662153 @default.
• W2016472144 cites W2112082948 @default.
• W2016472144 cites W2112650958 @default.
• W2016472144 cites W2116224448 @default.
• W2016472144 cites W2125062701 @default.
• W2016472144 cites W2135631433 @default.
• W2016472144 cites W2143001953 @default.
• W2016472144 cites W2143684964 @default.
• W2016472144 cites W2143954917 @default.
• W2016472144 cites W2146282879 @default.
• W2016472144 cites W2158495027 @default.
• W2016472144 cites W2163053670 @default.
• W2016472144 cites W2303651371 @default.
• W2016472144 cites W2484483641 @default.
• W2016472144 cites W75245760 @default.
• W2016472144 doi "https://doi.org/10.1371/journal.pone.0052438" @default.
• W2016472144 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3527505" @default.
• W2016472144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23285043" @default.
• W2016472144 hasPublicationYear "2012" @default.
• W2016472144 type Work @default.
• W2016472144 sameAs 2016472144 @default.
• W2016472144 citedByCount "62" @default.
• W2016472144 countsByYear W20164721442013 @default.
• W2016472144 countsByYear W20164721442014 @default.
• W2016472144 countsByYear W20164721442015 @default.
• W2016472144 countsByYear W20164721442016 @default.
• W2016472144 countsByYear W20164721442017 @default.
• W2016472144 countsByYear W20164721442018 @default.
• W2016472144 countsByYear W20164721442019 @default.
• W2016472144 countsByYear W20164721442020 @default.
• W2016472144 countsByYear W20164721442021 @default.
• W2016472144 countsByYear W20164721442022 @default.
• W2016472144 countsByYear W20164721442023 @default.
• W2016472144 crossrefType "journal-article" @default.
• W2016472144 hasAuthorship W2016472144A5000002986 @default.
• W2016472144 hasAuthorship W2016472144A5005451442 @default.
• W2016472144 hasAuthorship W2016472144A5005535605 @default.
• W2016472144 hasAuthorship W2016472144A5013373829 @default.
• W2016472144 hasAuthorship W2016472144A5016095791 @default.
• W2016472144 hasAuthorship W2016472144A5017836069 @default.
• W2016472144 hasAuthorship W2016472144A5023142491 @default.
• W2016472144 hasAuthorship W2016472144A5031245545 @default.
• W2016472144 hasAuthorship W2016472144A5036896719 @default.
• W2016472144 hasAuthorship W2016472144A5037853560 @default.
• W2016472144 hasAuthorship W2016472144A5078498803 @default.
• W2016472144 hasAuthorship W2016472144A5091160797 @default.
• W2016472144 hasBestOaLocation W20164721441 @default.
• W2016472144 hasConcept C126322002 @default.
• W2016472144 hasConcept C164705383 @default.
• W2016472144 hasConcept C17140001 @default.
• W2016472144 hasConcept C188816634 @default.
• W2016472144 hasConcept C207103383 @default.
• W2016472144 hasConcept C2778163477 @default.
• W2016472144 hasConcept C2779519902 @default.
• W2016472144 hasConcept C44249647 @default.
• W2016472144 hasConcept C71924100 @default.
• W2016472144 hasConcept C84393581 @default.
• W2016472144 hasConceptScore W2016472144C126322002 @default.
• W2016472144 hasConceptScore W2016472144C164705383 @default.
• W2016472144 hasConceptScore W2016472144C17140001 @default.
• W2016472144 hasConceptScore W2016472144C188816634 @default.
• W2016472144 hasConceptScore W2016472144C207103383 @default.
• W2016472144 hasConceptScore W2016472144C2778163477 @default.
• W2016472144 hasConceptScore W2016472144C2779519902 @default.
• W2016472144 hasConceptScore W2016472144C44249647 @default.
• W2016472144 hasConceptScore W2016472144C71924100 @default.
• W2016472144 hasConceptScore W2016472144C84393581 @default.
• W2016472144 hasIssue "12" @default.

• next