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- W2016500178 abstract "To the Editor: Since its introduction in 2007, ablative fractional photothermolysis (AFP) has been reported to be effective in improving appearance and texture in a broad array of skin conditions, including surgical, acne, and traumatic scars.1Cervelli V. Gentile P. Spallone D. Nicoli F. Verardi S. Petrocelli M. et al.Ultrapulsed fractional CO2 laser for the treatment of post-traumatic and pathological scars.J Drug Dermatol. 2010; 9: 1328-1331PubMed Google Scholar, 2Waibel J.S. Beer K.R. Ablative fractional resurfacing for the treatment of a third degree burn.J Drugs Dermatol. 2009; 8: 294-297PubMed Google Scholar A growing number of anecdotal reports have suggested that this laser modality can safely and effectively improve function in patients with debilitating scar contractures.3Shumaker P.R. Kwan J. Landers J.T. Uebelhoer N.S. Functional improvements in traumatic scars and scar contractures using an ablative fractional laser protocol.J Trauma Acute Care Surg. 2012; 73: S116-S121Crossref PubMed Scopus (54) Google Scholar, 4Anderson R.R. Donelan M.B. Hivnor C.H. Greeson E. Ross E.V. Shumaker P.R. et al.Laser treatment of traumatic scars with an emphasis on ablative fractional laser resurfacing: consensus report.JAMA Dermatol. 2014; 150: 187-193Crossref PubMed Scopus (178) Google Scholar, 5Uebelhoer N.S. Ross E.V. Shumaker P.R. Ablative fractional resurfacing for the treatment of traumatic scars.Semin Cutan Med Surg. 2012; 31: 110-120Crossref PubMed Scopus (37) Google Scholar However, to our knowledge there has not previously been a systematic evaluation of efficacy specifically related to function. In an institutional review board–approved retrospective review, we incorporated data from surgical, dermatologic, and occupational therapy records of patients who received AFP treatments to the forearm and wrist for scar contractures between October 1, 2009, and October 1, 2012. Our goal was to assess for statistically significant improvements in range of motion (ROM) after a course of AFP (Fig 1). Thirteen patients were identified with directly comparable ROM measurements before and after laser treatment. Mechanisms of injury included blasts from improvised explosive devices, burns, tumor extirpation, and sports accidents. Reconstructive techniques were variable and included open reduction and internal fixation, fasciotomy, flaps, and full and split-thickness skin grafts. The average age of eligible patients was 34 years. Median time to initial laser treatment after the injury or final surgery was 6.7 months. The average number of treatments per patient was 3.68 at an interval of 6 to 8 weeks. All treatments were performed with an ablative microfractionated carbon dioxide laser (UltraPulse Encore Deep Fx, Lumenis Ltd, Yokneam, Israel) with a treatment depth of approximately 1 to 2 mm (proportional to estimated scar thickness based largely on palpation) at the lowest density setting. The average time interval for comparison of ROM measurements was 7.85 months. Compared with pretreatment measurements, we observed an average increase in composite wrist (flexion/extension) and composite forearm (pronation/supination) ROM of 27.7 degrees and 16.8 degrees, respectively. This corresponded to a mean percentage improvement compared with baseline for the wrist and forearm of 39.9% and 22.5%. Median improvements compared with baseline were 26.3% (95% confidence interval 16.9%-61.8%, P = .004) and 11.1% (95% confidence interval 0%-53.4%, P = .019). Seven patients noted pain at the affected site before treatment and all of these noticed decreased pain or complete resolution after treatment. All patients noted subjective ROM improvements and functional gains consistent with objective measurements beginning with their first treatment. No complications including infection or worsening scarring were observed in the 74 treatments performed. This is, to our knowledge, the first systematic evaluation demonstrating statistically significant functional improvements after AFP in the setting of debilitating scar contractures. Limitations of the study include its retrospective nature and relatively small number of patients available for comparison. Although spontaneous improvement could have accounted for a portion of the observed improvements, most patients were referred after reaching a plateau with standard ROM protocols. Although future prospective controlled studies including larger numbers of patients and additional treatment locations are certainly required, AFP is a promising adjunct to existing contracture treatments including physical therapy and surgical revision. We would to thank Robert Riffenburgh, PhD, for his assistance with the statistical analysis." @default.
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- W2016500178 date "2014-10-01" @default.
- W2016500178 modified "2023-09-24" @default.
- W2016500178 title "Ablative fractional photothermolysis in the treatment of scar contractures of the wrists and forearms: A retrospective data analysis" @default.
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- W2016500178 doi "https://doi.org/10.1016/j.jaad.2014.06.002" @default.
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