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• W2016522268 abstract "Neonatal treatment of BALB/c mice with anti-VHT15 antibodies suppresses serum expression of VH T15 immunoglobulins in adult animals (2 months) which remains for over 8 months in half of the cases. Suppressed mice, however, contain control numbers of B cells expressing genes of the S107 VH family and producing VH T15 after mitogenic stimulation. Furthermore, immunization with phosphorylcholine (PC) breaks suppression and stimulates the production of VH T15 anti-PC antibodies. These animals, however, contain no detectable B lymphocytes expressing the T15 idiotype and produce no T15 idiotype-positive antibodies in response to PC. These results are discussed in the context of lymphocyte repertoire selection." @default.
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• W2016522268 date "1990-08-01" @default.
• W2016522268 modified "2023-10-18" @default.
• W2016522268 title "Divergency in the specificity of the induction and maintenance of neonatal suppression" @default.
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• W2016522268 doi "https://doi.org/10.1002/eji.1830200814" @default.
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