FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016556629> ?p ?o ?g. }

• W2016556629 endingPage "90" @default.
• W2016556629 startingPage "85" @default.
• W2016556629 abstract "The Shiga toxin-producing Escherichia coli (STEC) is an emerging foodborne pathogen. The proportion of cases attributed to STEC in an episode of diarrhea in the Faisalabad region of Pakistan was investigated. In addition, as increase in Shiga toxin (Stx) release after exposure to various antimicrobial agents is widely reported, we also elucidated the in vitro effects of three commonly used antibiotics (ampicillin, gentamicin, and cefotaxime) on Stx release. Isolation and detection of STEC was done using enzyme-linked immunosorbent assay and polymerase chain reaction, followed by phenotypic characterization. In vitro Stx release from isolated STEC was determined using enzyme-linked immunosorbent assay, and Stx-induced verocytotoxicity was quantified using cytotoxicity detection assay. STEC was detected in 5 (21.7%) of 23 patients. Exposure to minimum inhibitory concentration (MIC) of ampicillin, gentamicin, and cefotaxime resulted in a considerable decrease in toxin release and level of cytotoxicity in most of the STEC isolates when compared with control (without antibiotic exposure). Exposure to sub-MIC of ampicillin resulted in a relative increase in Stx release and cytotoxicity (p <or= 0.05) in three of the four isolates tested, whereas a decreasing trend was observed in isolates exposed to sub-MICs of gentamicin and cefotaxime. Sub-MIC of gentamicin resulted in largest decrease in Stx release and a similar trend was observed with cefotaxime to a lesser extent. In conclusion, these in vitro observations suggested that sub-MIC of ampicillin may stimulate Stx release and level of cytotoxicity and therefore should be avoided. Gentamicin did not show such effects and therefore may be considered for STEC antimicrobial therapy." @default.
• W2016556629 created "2016-06-24" @default.
• W2016556629 creator A5003392789 @default.
• W2016556629 creator A5005731285 @default.
• W2016556629 creator A5014111892 @default.
• W2016556629 creator A5022231290 @default.
• W2016556629 creator A5027385704 @default.
• W2016556629 creator A5049355886 @default.
• W2016556629 creator A5061699793 @default.
• W2016556629 creator A5074911591 @default.
• W2016556629 creator A5090242992 @default.
• W2016556629 date "2010-01-01" @default.
• W2016556629 modified "2023-10-10" @default.
• W2016556629 title "Effects of Ampicillin, Gentamicin, and Cefotaxime on the Release of Shiga Toxins from Shiga Toxin–Producing<i>Escherichia coli</i>Isolated During a Diarrhea Episode in Faisalabad, Pakistan" @default.
• W2016556629 cites W1536997383 @default.
• W2016556629 cites W1552890270 @default.
• W2016556629 cites W1964902749 @default.
• W2016556629 cites W1965346971 @default.
• W2016556629 cites W1974345521 @default.
• W2016556629 cites W1999027251 @default.
• W2016556629 cites W2026552624 @default.
• W2016556629 cites W2031623901 @default.
• W2016556629 cites W2039325385 @default.
• W2016556629 cites W2049878218 @default.
• W2016556629 cites W2055116729 @default.
• W2016556629 cites W2099514668 @default.
• W2016556629 cites W2101037240 @default.
• W2016556629 cites W2110212480 @default.
• W2016556629 cites W2122749943 @default.
• W2016556629 cites W2123805379 @default.
• W2016556629 cites W2132877052 @default.
• W2016556629 cites W2137994690 @default.
• W2016556629 cites W2150262463 @default.
• W2016556629 cites W2152964535 @default.
• W2016556629 cites W2156242960 @default.
• W2016556629 cites W2161908003 @default.
• W2016556629 cites W2324397673 @default.
• W2016556629 cites W2336647101 @default.
• W2016556629 cites W2461150461 @default.
• W2016556629 doi "https://doi.org/10.1089/fpd.2009.0311" @default.
• W2016556629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19785532" @default.
• W2016556629 hasPublicationYear "2010" @default.
• W2016556629 type Work @default.
• W2016556629 sameAs 2016556629 @default.
• W2016556629 citedByCount "24" @default.
• W2016556629 countsByYear W20165566292012 @default.
• W2016556629 countsByYear W20165566292013 @default.
• W2016556629 countsByYear W20165566292014 @default.
• W2016556629 countsByYear W20165566292015 @default.
• W2016556629 countsByYear W20165566292016 @default.
• W2016556629 countsByYear W20165566292017 @default.
• W2016556629 countsByYear W20165566292019 @default.
• W2016556629 countsByYear W20165566292021 @default.
• W2016556629 crossrefType "journal-article" @default.
• W2016556629 hasAuthorship W2016556629A5003392789 @default.
• W2016556629 hasAuthorship W2016556629A5005731285 @default.
• W2016556629 hasAuthorship W2016556629A5014111892 @default.
• W2016556629 hasAuthorship W2016556629A5022231290 @default.
• W2016556629 hasAuthorship W2016556629A5027385704 @default.
• W2016556629 hasAuthorship W2016556629A5049355886 @default.
• W2016556629 hasAuthorship W2016556629A5061699793 @default.
• W2016556629 hasAuthorship W2016556629A5074911591 @default.
• W2016556629 hasAuthorship W2016556629A5090242992 @default.
• W2016556629 hasConcept C104317684 @default.
• W2016556629 hasConcept C176947019 @default.
• W2016556629 hasConcept C185592680 @default.
• W2016556629 hasConcept C2775832221 @default.
• W2016556629 hasConcept C2776021129 @default.
• W2016556629 hasConcept C2778411228 @default.
• W2016556629 hasConcept C2778719061 @default.
• W2016556629 hasConcept C501593827 @default.
• W2016556629 hasConcept C547475151 @default.
• W2016556629 hasConcept C55493867 @default.
• W2016556629 hasConcept C86803240 @default.
• W2016556629 hasConcept C89423630 @default.
• W2016556629 hasConceptScore W2016556629C104317684 @default.
• W2016556629 hasConceptScore W2016556629C176947019 @default.
• W2016556629 hasConceptScore W2016556629C185592680 @default.
• W2016556629 hasConceptScore W2016556629C2775832221 @default.
• W2016556629 hasConceptScore W2016556629C2776021129 @default.
• W2016556629 hasConceptScore W2016556629C2778411228 @default.
• W2016556629 hasConceptScore W2016556629C2778719061 @default.
• W2016556629 hasConceptScore W2016556629C501593827 @default.
• W2016556629 hasConceptScore W2016556629C547475151 @default.
• W2016556629 hasConceptScore W2016556629C55493867 @default.
• W2016556629 hasConceptScore W2016556629C86803240 @default.
• W2016556629 hasConceptScore W2016556629C89423630 @default.
• W2016556629 hasIssue "1" @default.
• W2016556629 hasLocation W20165566291 @default.
• W2016556629 hasLocation W20165566292 @default.
• W2016556629 hasOpenAccess W2016556629 @default.
• W2016556629 hasPrimaryLocation W20165566291 @default.
• W2016556629 hasRelatedWork W100701909 @default.
• W2016556629 hasRelatedWork W123368106 @default.
• W2016556629 hasRelatedWork W1509974655 @default.
• W2016556629 hasRelatedWork W1999652102 @default.
• W2016556629 hasRelatedWork W2051932309 @default.
• W2016556629 hasRelatedWork W2087238066 @default.

• next