FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016561036> ?p ?o ?g. }

• W2016561036 endingPage "263" @default.
• W2016561036 startingPage "258" @default.
• W2016561036 abstract "The incidence of <i>Helicobacter pylori</i> and non-steroidal anti-inflammatory drug (NSAID)-negative peptic ulcer disease has increased over the last two decades, especially in the Western world and in countries with low <i>H. pylori</i> infection rates. Idiopathic peptic ulcer disease is a recently described entity which relates to peptic ulcers not caused by <i>H. pylori</i>, NSAID/aspirin therapy, other ulcerogenic organisms and drugs, or other rare malignant and benign diseases. Structural and secreted mucins create the unstirred gastric mucus layer and maintain a stable pH above the gastric mucosa. This mucous layer prevents enzymatic attack by acid and pepsin. Inhibition of cyclooxygenase by NSAID and aspirin inhibits prostaglandin production, inhibits mucin and bicarbonate secretion, and exposes the mucosa to the toxic effects of acid and intragastric enzymes. There is also a complex relationship between <i>H. pylori</i> and different mucin subtypes which on one hand facilitates mucin invasion but on the other hand protects the gastric mucosa. Genetic and epigenetic changes in the mucin molecule may be responsible for idiopathic peptic ulcer disease, but this hypothesis must be further investigated. Herein, the mucin hypothesis of idiopathic peptic ulcer disease is explored." @default.
• W2016561036 created "2016-06-24" @default.
• W2016561036 creator A5017345957 @default.
• W2016561036 creator A5055862445 @default.
• W2016561036 date "2012-01-01" @default.
• W2016561036 modified "2023-09-23" @default.
• W2016561036 title "Secreted and Membrane-Bound Mucins and Idiopathic Peptic Ulcer Disease" @default.
• W2016561036 cites W1505123947 @default.
• W2016561036 cites W1549501013 @default.
• W2016561036 cites W165344902 @default.
• W2016561036 cites W1967357055 @default.
• W2016561036 cites W1973067432 @default.
• W2016561036 cites W1973844632 @default.
• W2016561036 cites W1975453642 @default.
• W2016561036 cites W1976156488 @default.
• W2016561036 cites W1982594634 @default.
• W2016561036 cites W1984257229 @default.
• W2016561036 cites W1986868448 @default.
• W2016561036 cites W1989680903 @default.
• W2016561036 cites W2017020122 @default.
• W2016561036 cites W2017689825 @default.
• W2016561036 cites W2027341954 @default.
• W2016561036 cites W2044043374 @default.
• W2016561036 cites W2064672966 @default.
• W2016561036 cites W2079522249 @default.
• W2016561036 cites W2082738199 @default.
• W2016561036 cites W2086394884 @default.
• W2016561036 cites W2091586685 @default.
• W2016561036 cites W2105705896 @default.
• W2016561036 cites W2120950548 @default.
• W2016561036 cites W2122551120 @default.
• W2016561036 cites W2144554336 @default.
• W2016561036 cites W2150173080 @default.
• W2016561036 cites W2161254070 @default.
• W2016561036 cites W2161893481 @default.
• W2016561036 cites W2316568299 @default.
• W2016561036 cites W2326358513 @default.
• W2016561036 cites W4246596951 @default.
• W2016561036 cites W99131723 @default.
• W2016561036 doi "https://doi.org/10.1159/000341423" @default.
• W2016561036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23075498" @default.
• W2016561036 hasPublicationYear "2012" @default.
• W2016561036 type Work @default.
• W2016561036 sameAs 2016561036 @default.
• W2016561036 citedByCount "21" @default.
• W2016561036 countsByYear W20165610362013 @default.
• W2016561036 countsByYear W20165610362014 @default.
• W2016561036 countsByYear W20165610362015 @default.
• W2016561036 countsByYear W20165610362017 @default.
• W2016561036 countsByYear W20165610362018 @default.
• W2016561036 countsByYear W20165610362019 @default.
• W2016561036 countsByYear W20165610362020 @default.
• W2016561036 countsByYear W20165610362021 @default.
• W2016561036 countsByYear W20165610362022 @default.
• W2016561036 crossrefType "journal-article" @default.
• W2016561036 hasAuthorship W2016561036A5017345957 @default.
• W2016561036 hasAuthorship W2016561036A5055862445 @default.
• W2016561036 hasBestOaLocation W20165610361 @default.
• W2016561036 hasConcept C126322002 @default.
• W2016561036 hasConcept C142724271 @default.
• W2016561036 hasConcept C16311235 @default.
• W2016561036 hasConcept C179264091 @default.
• W2016561036 hasConcept C181199279 @default.
• W2016561036 hasConcept C185592680 @default.
• W2016561036 hasConcept C18903297 @default.
• W2016561036 hasConcept C203014093 @default.
• W2016561036 hasConcept C2776409635 @default.
• W2016561036 hasConcept C2777312293 @default.
• W2016561036 hasConcept C2777628954 @default.
• W2016561036 hasConcept C2779134260 @default.
• W2016561036 hasConcept C2779390736 @default.
• W2016561036 hasConcept C2779422922 @default.
• W2016561036 hasConcept C2780656511 @default.
• W2016561036 hasConcept C2781443798 @default.
• W2016561036 hasConcept C55493867 @default.
• W2016561036 hasConcept C71924100 @default.
• W2016561036 hasConcept C86803240 @default.
• W2016561036 hasConcept C90924648 @default.
• W2016561036 hasConceptScore W2016561036C126322002 @default.
• W2016561036 hasConceptScore W2016561036C142724271 @default.
• W2016561036 hasConceptScore W2016561036C16311235 @default.
• W2016561036 hasConceptScore W2016561036C179264091 @default.
• W2016561036 hasConceptScore W2016561036C181199279 @default.
• W2016561036 hasConceptScore W2016561036C185592680 @default.
• W2016561036 hasConceptScore W2016561036C18903297 @default.
• W2016561036 hasConceptScore W2016561036C203014093 @default.
• W2016561036 hasConceptScore W2016561036C2776409635 @default.
• W2016561036 hasConceptScore W2016561036C2777312293 @default.
• W2016561036 hasConceptScore W2016561036C2777628954 @default.
• W2016561036 hasConceptScore W2016561036C2779134260 @default.
• W2016561036 hasConceptScore W2016561036C2779390736 @default.
• W2016561036 hasConceptScore W2016561036C2779422922 @default.
• W2016561036 hasConceptScore W2016561036C2780656511 @default.
• W2016561036 hasConceptScore W2016561036C2781443798 @default.
• W2016561036 hasConceptScore W2016561036C55493867 @default.
• W2016561036 hasConceptScore W2016561036C71924100 @default.
• W2016561036 hasConceptScore W2016561036C86803240 @default.
• W2016561036 hasConceptScore W2016561036C90924648 @default.

• next