FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016591325> ?p ?o ?g. }

• W2016591325 endingPage "389" @default.
• W2016591325 startingPage "389" @default.
• W2016591325 abstract "Primary open-angle glaucoma, the most common form of glaucoma, is characterized by irreversible loss of axons from the optic nerve. Previous research in humans and monkeys with glaucoma suggests that the site of damage to the axons is at the level of the lamina cribrosa in the optic nerve head. In the glaucomatous optic nerve head, progressive cupping of the optic disc results from compression, stretching, and remodeling of the connective tissue (extracellular matrix) of the lamina cribrosa. Astrocytes are the major cell type in the optic nerve and may participate actively in the remodeling of the extracellular matrix. There may be individual variability in the composition, structure, or reactive processes of the tissue supporting the axons in the optic nerve that may explain the variations in the nature and degree of cupping in response to intraocular pressure and in the progression of the neuropathy. We present evidence of specific changes in the extracellular matrix of the lamina cribrosa and the role of astrocytes in glaucomatous optic neuropathy. Future studies focused on developing therapies directed at preventing or controling damage to the extracellular matrix may help improve the outcome of the management of glaucoma." @default.
• W2016591325 created "2016-06-24" @default.
• W2016591325 creator A5039923277 @default.
• W2016591325 creator A5068316978 @default.
• W2016591325 date "1997-03-01" @default.
• W2016591325 modified "2023-10-03" @default.
• W2016591325 title "The Optic Nerve Head in Glaucomatous Optic Neuropathy" @default.
• W2016591325 cites W110045858 @default.
• W2016591325 cites W164868962 @default.
• W2016591325 cites W1829106046 @default.
• W2016591325 cites W1964458657 @default.
• W2016591325 cites W1964726904 @default.
• W2016591325 cites W1966170741 @default.
• W2016591325 cites W1967095650 @default.
• W2016591325 cites W1968143827 @default.
• W2016591325 cites W1983919643 @default.
• W2016591325 cites W1987984585 @default.
• W2016591325 cites W1992717708 @default.
• W2016591325 cites W1996965420 @default.
• W2016591325 cites W2006207066 @default.
• W2016591325 cites W2006289803 @default.
• W2016591325 cites W2016784489 @default.
• W2016591325 cites W2017315950 @default.
• W2016591325 cites W2018481422 @default.
• W2016591325 cites W2021850271 @default.
• W2016591325 cites W2023000923 @default.
• W2016591325 cites W2023949430 @default.
• W2016591325 cites W2032895185 @default.
• W2016591325 cites W2033158622 @default.
• W2016591325 cites W2049278931 @default.
• W2016591325 cites W2050632988 @default.
• W2016591325 cites W2054703329 @default.
• W2016591325 cites W2055259320 @default.
• W2016591325 cites W2056608087 @default.
• W2016591325 cites W2061297727 @default.
• W2016591325 cites W2073698327 @default.
• W2016591325 cites W2074706462 @default.
• W2016591325 cites W2081118124 @default.
• W2016591325 cites W2082299986 @default.
• W2016591325 cites W2084941189 @default.
• W2016591325 cites W2095219890 @default.
• W2016591325 cites W2098892195 @default.
• W2016591325 cites W2100124039 @default.
• W2016591325 cites W2105686119 @default.
• W2016591325 cites W2109591052 @default.
• W2016591325 cites W2118076209 @default.
• W2016591325 cites W2120256127 @default.
• W2016591325 cites W2122322025 @default.
• W2016591325 cites W2123457508 @default.
• W2016591325 cites W2137171312 @default.
• W2016591325 cites W2159459710 @default.
• W2016591325 cites W2166752018 @default.
• W2016591325 cites W2169079679 @default.
• W2016591325 cites W2469767810 @default.
• W2016591325 cites W2885158702 @default.
• W2016591325 cites W80270903 @default.
• W2016591325 cites W99027208 @default.
• W2016591325 doi "https://doi.org/10.1001/archopht.1997.01100150391013" @default.
• W2016591325 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9076213" @default.
• W2016591325 hasPublicationYear "1997" @default.
• W2016591325 type Work @default.
• W2016591325 sameAs 2016591325 @default.
• W2016591325 citedByCount "188" @default.
• W2016591325 countsByYear W20165913252012 @default.
• W2016591325 countsByYear W20165913252013 @default.
• W2016591325 countsByYear W20165913252014 @default.
• W2016591325 countsByYear W20165913252015 @default.
• W2016591325 countsByYear W20165913252016 @default.
• W2016591325 countsByYear W20165913252017 @default.
• W2016591325 countsByYear W20165913252019 @default.
• W2016591325 countsByYear W20165913252020 @default.
• W2016591325 countsByYear W20165913252021 @default.
• W2016591325 countsByYear W20165913252022 @default.
• W2016591325 countsByYear W20165913252023 @default.
• W2016591325 crossrefType "journal-article" @default.
• W2016591325 hasAuthorship W2016591325A5039923277 @default.
• W2016591325 hasAuthorship W2016591325A5068316978 @default.
• W2016591325 hasConcept C104317684 @default.
• W2016591325 hasConcept C105702510 @default.
• W2016591325 hasConcept C114696181 @default.
• W2016591325 hasConcept C118487528 @default.
• W2016591325 hasConcept C127716648 @default.
• W2016591325 hasConcept C189165786 @default.
• W2016591325 hasConcept C2777989353 @default.
• W2016591325 hasConcept C2778233873 @default.
• W2016591325 hasConcept C2778527774 @default.
• W2016591325 hasConcept C2779735895 @default.
• W2016591325 hasConcept C2780837183 @default.
• W2016591325 hasConcept C2781092963 @default.
• W2016591325 hasConcept C2983497740 @default.
• W2016591325 hasConcept C55493867 @default.
• W2016591325 hasConcept C71924100 @default.
• W2016591325 hasConcept C86803240 @default.
• W2016591325 hasConcept C95444343 @default.
• W2016591325 hasConcept C96021297 @default.
• W2016591325 hasConceptScore W2016591325C104317684 @default.
• W2016591325 hasConceptScore W2016591325C105702510 @default.
• W2016591325 hasConceptScore W2016591325C114696181 @default.

• next