FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016609809> ?p ?o ?g. }

• W2016609809 endingPage "554" @default.
• W2016609809 startingPage "549" @default.
• W2016609809 abstract "In our previous studies we found that cyclopentenane prostaglandin A1 (PGA1) had neuroprotective effects in a rodent ischemic model. In the present study we aimed to investigate the inhibitory effect of PGA 1 on platelet function. The rate of aggregation of human platelets was measured by using turbidimetry. The rate of adhesion of platelets to cultured endothelial cells was determined by using [3H]-adenine labeled platelets. 5-Hydroxytryptamine release from platelets was measured with O-phthaldialdehyde fluorospectrophotometry. The levels of TXB2, a stable metabolite of TXA2, were determined by radioimmunoassay. Alternations in platelet morphology were observed using an electron microscope, and the intraplatelet free calcium concentrations were measured with Fluo-3/AM FCM assay. PGA1 significantly inhibited thrombin-, collagen- and ADP-induced aggregation and adhesion of platelets. The morphological changes of platelets induced by thrombin were blocked by PGA1. PGA1 inhibited the release of 5-hydroxytyptamine from dense granules and the synthesis of TXA2. PGA1 inhibits the activation of platelets probably through blocking increases in intracellular calcium concentration and TXA2 synthesis." @default.
• W2016609809 created "2016-06-24" @default.
• W2016609809 creator A5041287759 @default.
• W2016609809 creator A5061796012 @default.
• W2016609809 creator A5062429074 @default.
• W2016609809 creator A5063399497 @default.
• W2016609809 creator A5065716081 @default.
• W2016609809 date "2006-05-01" @default.
• W2016609809 modified "2023-10-16" @default.
• W2016609809 title "Prostaglandin A1 inhibits increases in intracellular calcium concentration, TXA2 production and platelet activation1" @default.
• W2016609809 cites W1531169077 @default.
• W2016609809 cites W1586931401 @default.
• W2016609809 cites W1904788586 @default.
• W2016609809 cites W1968658257 @default.
• W2016609809 cites W1996267589 @default.
• W2016609809 cites W2001825870 @default.
• W2016609809 cites W2007758955 @default.
• W2016609809 cites W2027484290 @default.
• W2016609809 cites W2033271596 @default.
• W2016609809 cites W2039351502 @default.
• W2016609809 cites W2052245900 @default.
• W2016609809 cites W2055703298 @default.
• W2016609809 cites W2061296910 @default.
• W2016609809 cites W2063636083 @default.
• W2016609809 cites W2082238907 @default.
• W2016609809 cites W2092103542 @default.
• W2016609809 cites W2114437978 @default.
• W2016609809 cites W2123200480 @default.
• W2016609809 cites W2136301213 @default.
• W2016609809 cites W2157262487 @default.
• W2016609809 cites W2158960911 @default.
• W2016609809 cites W2412630367 @default.
• W2016609809 cites W4240789623 @default.
• W2016609809 cites W4362204104 @default.
• W2016609809 cites W2037007306 @default.
• W2016609809 doi "https://doi.org/10.1111/j.1745-7254.2006.00311.x" @default.
• W2016609809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16626509" @default.
• W2016609809 hasPublicationYear "2006" @default.
• W2016609809 type Work @default.
• W2016609809 sameAs 2016609809 @default.
• W2016609809 citedByCount "7" @default.
• W2016609809 countsByYear W20166098092014 @default.
• W2016609809 countsByYear W20166098092019 @default.
• W2016609809 countsByYear W20166098092020 @default.
• W2016609809 countsByYear W20166098092023 @default.
• W2016609809 crossrefType "journal-article" @default.
• W2016609809 hasAuthorship W2016609809A5041287759 @default.
• W2016609809 hasAuthorship W2016609809A5061796012 @default.
• W2016609809 hasAuthorship W2016609809A5062429074 @default.
• W2016609809 hasAuthorship W2016609809A5063399497 @default.
• W2016609809 hasAuthorship W2016609809A5065716081 @default.
• W2016609809 hasBestOaLocation W20166098091 @default.
• W2016609809 hasConcept C12554922 @default.
• W2016609809 hasConcept C126322002 @default.
• W2016609809 hasConcept C176685330 @default.
• W2016609809 hasConcept C178790620 @default.
• W2016609809 hasConcept C181080969 @default.
• W2016609809 hasConcept C185592680 @default.
• W2016609809 hasConcept C2777292125 @default.
• W2016609809 hasConcept C2780664492 @default.
• W2016609809 hasConcept C2780777798 @default.
• W2016609809 hasConcept C2781024287 @default.
• W2016609809 hasConcept C2781080829 @default.
• W2016609809 hasConcept C3018697912 @default.
• W2016609809 hasConcept C519063684 @default.
• W2016609809 hasConcept C55493867 @default.
• W2016609809 hasConcept C71924100 @default.
• W2016609809 hasConcept C79879829 @default.
• W2016609809 hasConcept C84416704 @default.
• W2016609809 hasConcept C86803240 @default.
• W2016609809 hasConcept C89560881 @default.
• W2016609809 hasConceptScore W2016609809C12554922 @default.
• W2016609809 hasConceptScore W2016609809C126322002 @default.
• W2016609809 hasConceptScore W2016609809C176685330 @default.
• W2016609809 hasConceptScore W2016609809C178790620 @default.
• W2016609809 hasConceptScore W2016609809C181080969 @default.
• W2016609809 hasConceptScore W2016609809C185592680 @default.
• W2016609809 hasConceptScore W2016609809C2777292125 @default.
• W2016609809 hasConceptScore W2016609809C2780664492 @default.
• W2016609809 hasConceptScore W2016609809C2780777798 @default.
• W2016609809 hasConceptScore W2016609809C2781024287 @default.
• W2016609809 hasConceptScore W2016609809C2781080829 @default.
• W2016609809 hasConceptScore W2016609809C3018697912 @default.
• W2016609809 hasConceptScore W2016609809C519063684 @default.
• W2016609809 hasConceptScore W2016609809C55493867 @default.
• W2016609809 hasConceptScore W2016609809C71924100 @default.
• W2016609809 hasConceptScore W2016609809C79879829 @default.
• W2016609809 hasConceptScore W2016609809C84416704 @default.
• W2016609809 hasConceptScore W2016609809C86803240 @default.
• W2016609809 hasConceptScore W2016609809C89560881 @default.
• W2016609809 hasIssue "5" @default.
• W2016609809 hasLocation W20166098091 @default.
• W2016609809 hasLocation W20166098092 @default.
• W2016609809 hasOpenAccess W2016609809 @default.
• W2016609809 hasPrimaryLocation W20166098091 @default.
• W2016609809 hasRelatedWork W154881089 @default.
• W2016609809 hasRelatedWork W2016609809 @default.
• W2016609809 hasRelatedWork W2061171052 @default.

• next