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- W2016634712 abstract "The nucleotide sequence is reported of a cDNA clone encoding aCaenorhabditis eleganshomolog of guinea pig and human alkyl-dihydroxyacetonephosphate synthase. The open reading frame encodes a protein of 597 amino acids which shows extensive homology with the mammalian enzymes (52% identical and about 76% similar in the overlapping region). In contrast to the mammalian enzymes, which carry a consensus peroxisomal targeting signal type 2 in a cleavable N-terminal presequence, thisCaenorhabditis eleganshomolog carries a consensus peroxisomal targeting signal type 1 (CKL) at its C-terminus. Expression of this protein in anin vitrotranscription/translation system yielded a 65 kDa protein. Recombinantaenorhabditis elegansalkyl-DHAP synthase expressed in the yeastPichia pastoriswas enzymatically active." @default.
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- W2016634712 title "Nucleotide Sequence of a cDNA Clone Encoding aCaenorhabditis elegansHomolog of Mammalian Alkyl-Dihydroxyacetonephosphate Synthase: Evolutionary Switching of Peroxisomal Targeting Signals" @default.
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- W2016634712 doi "https://doi.org/10.1006/bbrc.1997.7950" @default.
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