FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016649620> ?p ?o ?g. }

• W2016649620 endingPage "1058" @default.
• W2016649620 startingPage "1053" @default.
• W2016649620 abstract "The defense system of aortic endothelial cells against oxidative stress was studied in alloxan-induced diabetic rabbits, and the effect of insulin on the antioxidant activities was estimated. Endothelial cells were prepared from 10 diabetic rabbits, 18 diabetic rabbits treated with insulin, and 10 age-matched controls after 17 days of diabetes. These cells were used for the estimation of glutathione (GSH) levels and its related enzyme activities. The antioxidant activities in these endothelial cells from diabetic rabbits were compared with those from control subjects. The concentration of GSH decreased in diabetic rabbits (1.6 +/- 0.2 nmol/mg protein [mean +/- SD] v 3.7 +/- 0.6 nmol/mg protein). Decreases in the activities of Cu, Zn-superoxide dismutase (Cu,Zn-SOD) (62.7 +/- 11.0 U/mg protein v 172.9 +/- 20.2 U/mg protein), catalase (7.6 +/- 2.1 U/mg protein v 12.3 +/- 3.2 U/mg protein), and GSH peroxidase (134.0 +/- 27.0 mU/mg protein v 179.1 +/- 26.2 mU/mg protein) were observed. The activities of other GSH-related enzymes such as GSH S-transferase or GSH reductase did not change in endothelial cells from diabetic rabbits. Most of these antioxidant activities were prevented when diabetic rabbits were treated with insulin (1 to 2 U/kg/d). These antioxidant activities were also determined in the diabetic liver and kidney. Similar decreases in the cellular defense activities and prevention of the decrease in activities by insulin were observed in the diabetic liver, while these antioxidant enzyme activities in the kidney were resistant to diabetic conditions.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W2016649620 created "2016-06-24" @default.
• W2016649620 creator A5011601287 @default.
• W2016649620 creator A5022380234 @default.
• W2016649620 creator A5037780357 @default.
• W2016649620 creator A5066969352 @default.
• W2016649620 creator A5081174788 @default.
• W2016649620 creator A5083509830 @default.
• W2016649620 date "1992-10-01" @default.
• W2016649620 modified "2023-10-18" @default.
• W2016649620 title "Effect of insulin on impaired antioxidant activities in aortic endothelial cells from diabetic rabbits" @default.
• W2016649620 cites W1482287596 @default.
• W2016649620 cites W1552457962 @default.
• W2016649620 cites W1562066535 @default.
• W2016649620 cites W1563605533 @default.
• W2016649620 cites W1775749144 @default.
• W2016649620 cites W1940436875 @default.
• W2016649620 cites W1973457829 @default.
• W2016649620 cites W1996066410 @default.
• W2016649620 cites W2003599469 @default.
• W2016649620 cites W2011383364 @default.
• W2016649620 cites W2026085321 @default.
• W2016649620 cites W2033413068 @default.
• W2016649620 cites W2043441850 @default.
• W2016649620 cites W2053527204 @default.
• W2016649620 cites W2057204560 @default.
• W2016649620 cites W2065145370 @default.
• W2016649620 cites W2080785720 @default.
• W2016649620 cites W2083687879 @default.
• W2016649620 cites W2094992873 @default.
• W2016649620 cites W2095214547 @default.
• W2016649620 cites W2101422765 @default.
• W2016649620 cites W2111653865 @default.
• W2016649620 cites W2123619121 @default.
• W2016649620 cites W2169182236 @default.
• W2016649620 cites W2989138034 @default.
• W2016649620 cites W4245957869 @default.
• W2016649620 cites W4246215879 @default.
• W2016649620 doi "https://doi.org/10.1016/0026-0495(92)90285-i" @default.
• W2016649620 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1406292" @default.
• W2016649620 hasPublicationYear "1992" @default.
• W2016649620 type Work @default.
• W2016649620 sameAs 2016649620 @default.
• W2016649620 citedByCount "85" @default.
• W2016649620 countsByYear W20166496202012 @default.
• W2016649620 countsByYear W20166496202013 @default.
• W2016649620 countsByYear W20166496202014 @default.
• W2016649620 countsByYear W20166496202015 @default.
• W2016649620 countsByYear W20166496202016 @default.
• W2016649620 crossrefType "journal-article" @default.
• W2016649620 hasAuthorship W2016649620A5011601287 @default.
• W2016649620 hasAuthorship W2016649620A5022380234 @default.
• W2016649620 hasAuthorship W2016649620A5037780357 @default.
• W2016649620 hasAuthorship W2016649620A5066969352 @default.
• W2016649620 hasAuthorship W2016649620A5081174788 @default.
• W2016649620 hasAuthorship W2016649620A5083509830 @default.
• W2016649620 hasConcept C126322002 @default.
• W2016649620 hasConcept C134018914 @default.
• W2016649620 hasConcept C165069038 @default.
• W2016649620 hasConcept C181199279 @default.
• W2016649620 hasConcept C185592680 @default.
• W2016649620 hasConcept C2775838275 @default.
• W2016649620 hasConcept C2776151105 @default.
• W2016649620 hasConcept C2778004101 @default.
• W2016649620 hasConcept C2778760513 @default.
• W2016649620 hasConcept C2778979269 @default.
• W2016649620 hasConcept C2779306644 @default.
• W2016649620 hasConcept C2781005915 @default.
• W2016649620 hasConcept C538909803 @default.
• W2016649620 hasConcept C55493867 @default.
• W2016649620 hasConcept C555293320 @default.
• W2016649620 hasConcept C71924100 @default.
• W2016649620 hasConceptScore W2016649620C126322002 @default.
• W2016649620 hasConceptScore W2016649620C134018914 @default.
• W2016649620 hasConceptScore W2016649620C165069038 @default.
• W2016649620 hasConceptScore W2016649620C181199279 @default.
• W2016649620 hasConceptScore W2016649620C185592680 @default.
• W2016649620 hasConceptScore W2016649620C2775838275 @default.
• W2016649620 hasConceptScore W2016649620C2776151105 @default.
• W2016649620 hasConceptScore W2016649620C2778004101 @default.
• W2016649620 hasConceptScore W2016649620C2778760513 @default.
• W2016649620 hasConceptScore W2016649620C2778979269 @default.
• W2016649620 hasConceptScore W2016649620C2779306644 @default.
• W2016649620 hasConceptScore W2016649620C2781005915 @default.
• W2016649620 hasConceptScore W2016649620C538909803 @default.
• W2016649620 hasConceptScore W2016649620C55493867 @default.
• W2016649620 hasConceptScore W2016649620C555293320 @default.
• W2016649620 hasConceptScore W2016649620C71924100 @default.
• W2016649620 hasIssue "10" @default.
• W2016649620 hasLocation W20166496201 @default.
• W2016649620 hasLocation W20166496202 @default.
• W2016649620 hasOpenAccess W2016649620 @default.
• W2016649620 hasPrimaryLocation W20166496201 @default.
• W2016649620 hasRelatedWork W159419932 @default.
• W2016649620 hasRelatedWork W1969555927 @default.
• W2016649620 hasRelatedWork W2090665895 @default.
• W2016649620 hasRelatedWork W2356844915 @default.
• W2016649620 hasRelatedWork W2415799310 @default.

• next