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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016651241> ?p ?o ?g. }

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• W2016651241 abstract "Microspinosamide (1), a new cyclic depsipeptide incorporating 13 amino acid residues, was isolated from extracts of an Indonesian collection of the marine sponge Sidonops microspinosa. Its structure was elucidated by extensive NMR and mass spectral analyses, and by chemical degradation and derivatization studies. The tridecapeptide 1 incorporates numerous uncommon amino acids, and it is the first naturally occurring peptide to contain a beta-hydroxy-p-bromophenylalanine residue. Microspinosamide (1) inhibited the cytopathic effect of HIV-1 infection in an XTT-based in vitro assay with an EC(50) value of approximately 0.2 microg/mL." @default.
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• W2016651241 date "2000-12-12" @default.
• W2016651241 modified "2023-10-15" @default.
• W2016651241 title "Microspinosamide, a New HIV-Inhibitory Cyclic Depsipeptide from the Marine Sponge <i>Sidonops </i><i>m</i><i>icrospinosa</i>" @default.
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• W2016651241 doi "https://doi.org/10.1021/np0002379" @default.
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