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- W2016664580 abstract "A range of alternative radical macrocyclisation approaches to cembranoids have been evaluated. Radical macrocyclisations involving the allylic radicals 11 generated from the corresponding allylic iodides, 15b and 20b, in the presence of Bu3SnH–AIBN, are shown to lead to 14-membered trienones, viz10, via selective 14-endo-trig processes. Both 10a and 10b can then be elaborated to the natural marine cembranoids 8(mukulol) and 9 respectively, by straightforward functional group interconversions." @default.
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- W2016664580 date "1992-01-01" @default.
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- W2016664580 title "Macrocyclisations using allylic radical intermediates. A new synthetic approach to natural 14-membered cembranoids" @default.
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- W2016664580 doi "https://doi.org/10.1039/p19920001313" @default.
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