Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016670512> ?p ?o ?g. }
- W2016670512 endingPage "60" @default.
- W2016670512 startingPage "52" @default.
- W2016670512 abstract "A new mass spectrometric technique, charge reduction electrospray mass spectrometry (CREMS), allowing the analysis of complex mixtures of biological molecules is described. The charge state of ions produced by electrospray ionization may be reduced in a controlled manner to yield predominantly singly charged ions through reactions with bipolar (i.e., both positively and negatively charged) ions generated using a 210Po alpha particle source. The electrospray-generated multiply charged ions undergo charge reduction in a neutralization chamber positioned before the entrance nozzle to the mass spectrometer. The ions are detected using a commercial orthogonal electrospray time-of-flight mass spectrometer, although the neutralization chamber can be adapted to virtually any mass analyzer. The CREMS results obtained exhibit a signal intensity drop-off with increasing oligonucleotide size similar to that observed with matrix-assisted laser desorption/ionization mass spectrometry. Proton-transfer reactions were found to be responsible for reducing charge on proteins and oligonucleotides in both positive and negative ion mode." @default.
- W2016670512 created "2016-06-24" @default.
- W2016670512 creator A5006873729 @default.
- W2016670512 creator A5007686133 @default.
- W2016670512 creator A5022080753 @default.
- W2016670512 date "1999-12-03" @default.
- W2016670512 modified "2023-10-16" @default.
- W2016670512 title "Charge Reduction Electrospray Mass Spectrometry" @default.
- W2016670512 cites W1965671819 @default.
- W2016670512 cites W1966985858 @default.
- W2016670512 cites W1967404694 @default.
- W2016670512 cites W1969496086 @default.
- W2016670512 cites W1970025816 @default.
- W2016670512 cites W1970070502 @default.
- W2016670512 cites W1973486893 @default.
- W2016670512 cites W1974830441 @default.
- W2016670512 cites W1977628837 @default.
- W2016670512 cites W1986547820 @default.
- W2016670512 cites W1989906952 @default.
- W2016670512 cites W1998734835 @default.
- W2016670512 cites W2013279633 @default.
- W2016670512 cites W2014140929 @default.
- W2016670512 cites W2016297089 @default.
- W2016670512 cites W2026214789 @default.
- W2016670512 cites W2030043624 @default.
- W2016670512 cites W2037549368 @default.
- W2016670512 cites W2043250176 @default.
- W2016670512 cites W2052535793 @default.
- W2016670512 cites W2054838229 @default.
- W2016670512 cites W2055146558 @default.
- W2016670512 cites W2059368838 @default.
- W2016670512 cites W2063936868 @default.
- W2016670512 cites W2072671787 @default.
- W2016670512 cites W2073155155 @default.
- W2016670512 cites W2075635075 @default.
- W2016670512 cites W2084035299 @default.
- W2016670512 cites W2089111655 @default.
- W2016670512 cites W2090006460 @default.
- W2016670512 cites W2091851551 @default.
- W2016670512 cites W2124816512 @default.
- W2016670512 cites W2138706632 @default.
- W2016670512 cites W2146664247 @default.
- W2016670512 cites W247726684 @default.
- W2016670512 doi "https://doi.org/10.1021/ac990878c" @default.
- W2016670512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10655634" @default.
- W2016670512 hasPublicationYear "1999" @default.
- W2016670512 type Work @default.
- W2016670512 sameAs 2016670512 @default.
- W2016670512 citedByCount "134" @default.
- W2016670512 countsByYear W20166705122013 @default.
- W2016670512 countsByYear W20166705122014 @default.
- W2016670512 countsByYear W20166705122015 @default.
- W2016670512 countsByYear W20166705122016 @default.
- W2016670512 countsByYear W20166705122017 @default.
- W2016670512 countsByYear W20166705122018 @default.
- W2016670512 countsByYear W20166705122019 @default.
- W2016670512 countsByYear W20166705122020 @default.
- W2016670512 countsByYear W20166705122021 @default.
- W2016670512 countsByYear W20166705122022 @default.
- W2016670512 countsByYear W20166705122023 @default.
- W2016670512 crossrefType "journal-article" @default.
- W2016670512 hasAuthorship W2016670512A5006873729 @default.
- W2016670512 hasAuthorship W2016670512A5007686133 @default.
- W2016670512 hasAuthorship W2016670512A5022080753 @default.
- W2016670512 hasConcept C113196181 @default.
- W2016670512 hasConcept C13762613 @default.
- W2016670512 hasConcept C145148216 @default.
- W2016670512 hasConcept C162356407 @default.
- W2016670512 hasConcept C16291436 @default.
- W2016670512 hasConcept C167050937 @default.
- W2016670512 hasConcept C178790620 @default.
- W2016670512 hasConcept C185592680 @default.
- W2016670512 hasConcept C188224857 @default.
- W2016670512 hasConcept C194451485 @default.
- W2016670512 hasConcept C198291218 @default.
- W2016670512 hasConcept C202157981 @default.
- W2016670512 hasConcept C40684141 @default.
- W2016670512 hasConcept C43617362 @default.
- W2016670512 hasConcept C75233609 @default.
- W2016670512 hasConceptScore W2016670512C113196181 @default.
- W2016670512 hasConceptScore W2016670512C13762613 @default.
- W2016670512 hasConceptScore W2016670512C145148216 @default.
- W2016670512 hasConceptScore W2016670512C162356407 @default.
- W2016670512 hasConceptScore W2016670512C16291436 @default.
- W2016670512 hasConceptScore W2016670512C167050937 @default.
- W2016670512 hasConceptScore W2016670512C178790620 @default.
- W2016670512 hasConceptScore W2016670512C185592680 @default.
- W2016670512 hasConceptScore W2016670512C188224857 @default.
- W2016670512 hasConceptScore W2016670512C194451485 @default.
- W2016670512 hasConceptScore W2016670512C198291218 @default.
- W2016670512 hasConceptScore W2016670512C202157981 @default.
- W2016670512 hasConceptScore W2016670512C40684141 @default.
- W2016670512 hasConceptScore W2016670512C43617362 @default.
- W2016670512 hasConceptScore W2016670512C75233609 @default.
- W2016670512 hasIssue "1" @default.
- W2016670512 hasLocation W20166705121 @default.
- W2016670512 hasLocation W20166705122 @default.
- W2016670512 hasOpenAccess W2016670512 @default.