FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016674979> ?p ?o ?g. }

• W2016674979 endingPage "320" @default.
• W2016674979 startingPage "314" @default.
• W2016674979 abstract "HIV drug resistance (DR) testing using Sanger sequencing (SS) is limited by the inability of the method to identify low abundance drug resistance variants. The application of tagged pooled pyrosequencing (TPP) for HIV DR surveillance is described and the results compared with SS. HIV(+) serum specimens were genotyped using both SS and TPP. Surveillance drug resistance mutations were identified using SS and TPP consensus reads at multiple mixed base identification thresholds (MBITs). Drug resistance patterns were highly concordant between SS and TPP when the MBIT was set at 20%. DR mutations were detected in 7.1% of the subjects, with 1.6% of individuals harboring resistance to NRTI, 3.3% NNRTI and 2.7% PI. Analyzing the TPP reads for each subject confirmed that drug resistance mutations with frequencies <20% were inconsistently detected by SS. Conversely, low abundance drug resistant variants were easily identified using TPP with mixed base identification threshold set at low value. In conclusion, at considerable savings when compared to commercial assays, TPP produces HIV DR profiles that are concordant with those from SS, furthermore, these same data can be used to identify low abundance drug resistant variants." @default.
• W2016674979 created "2016-06-24" @default.
• W2016674979 creator A5008793716 @default.
• W2016674979 creator A5014466817 @default.
• W2016674979 creator A5027089352 @default.
• W2016674979 creator A5028900793 @default.
• W2016674979 creator A5035513797 @default.
• W2016674979 creator A5045810852 @default.
• W2016674979 creator A5061367689 @default.
• W2016674979 creator A5072588007 @default.
• W2016674979 creator A5088735539 @default.
• W2016674979 date "2013-02-01" @default.
• W2016674979 modified "2023-09-26" @default.
• W2016674979 title "Low abundance drug resistance variants in transmitted HIV drug resistance surveillance specimens identified using tagged pooled pyrosequencing" @default.
• W2016674979 cites W1524252975 @default.
• W2016674979 cites W1966063036 @default.
• W2016674979 cites W1982600050 @default.
• W2016674979 cites W1988632009 @default.
• W2016674979 cites W1991893197 @default.
• W2016674979 cites W2004293828 @default.
• W2016674979 cites W202026658 @default.
• W2016674979 cites W2032847961 @default.
• W2016674979 cites W2036549899 @default.
• W2016674979 cites W2043876130 @default.
• W2016674979 cites W2051548413 @default.
• W2016674979 cites W2053485968 @default.
• W2016674979 cites W2054162676 @default.
• W2016674979 cites W2057977668 @default.
• W2016674979 cites W2061680337 @default.
• W2016674979 cites W2063600611 @default.
• W2016674979 cites W2066452478 @default.
• W2016674979 cites W2077956544 @default.
• W2016674979 cites W2084793748 @default.
• W2016674979 cites W2086729134 @default.
• W2016674979 cites W2096310657 @default.
• W2016674979 cites W2102351707 @default.
• W2016674979 cites W2109046728 @default.
• W2016674979 cites W2111988768 @default.
• W2016674979 cites W2123613937 @default.
• W2016674979 cites W2128114769 @default.
• W2016674979 cites W2128327031 @default.
• W2016674979 cites W2132050166 @default.
• W2016674979 cites W2136683144 @default.
• W2016674979 cites W2141287414 @default.
• W2016674979 cites W2147247273 @default.
• W2016674979 cites W2164762627 @default.
• W2016674979 cites W2318289184 @default.
• W2016674979 cites W3196876339 @default.
• W2016674979 doi "https://doi.org/10.1016/j.jviromet.2012.10.018" @default.
• W2016674979 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23159670" @default.
• W2016674979 hasPublicationYear "2013" @default.
• W2016674979 type Work @default.
• W2016674979 sameAs 2016674979 @default.
• W2016674979 citedByCount "10" @default.
• W2016674979 countsByYear W20166749792013 @default.
• W2016674979 countsByYear W20166749792014 @default.
• W2016674979 countsByYear W20166749792015 @default.
• W2016674979 countsByYear W20166749792018 @default.
• W2016674979 countsByYear W20166749792019 @default.
• W2016674979 countsByYear W20166749792020 @default.
• W2016674979 crossrefType "journal-article" @default.
• W2016674979 hasAuthorship W2016674979A5008793716 @default.
• W2016674979 hasAuthorship W2016674979A5014466817 @default.
• W2016674979 hasAuthorship W2016674979A5027089352 @default.
• W2016674979 hasAuthorship W2016674979A5028900793 @default.
• W2016674979 hasAuthorship W2016674979A5035513797 @default.
• W2016674979 hasAuthorship W2016674979A5045810852 @default.
• W2016674979 hasAuthorship W2016674979A5061367689 @default.
• W2016674979 hasAuthorship W2016674979A5072588007 @default.
• W2016674979 hasAuthorship W2016674979A5088735539 @default.
• W2016674979 hasConcept C104317684 @default.
• W2016674979 hasConcept C114851261 @default.
• W2016674979 hasConcept C125009961 @default.
• W2016674979 hasConcept C142462285 @default.
• W2016674979 hasConcept C159047783 @default.
• W2016674979 hasConcept C2778451633 @default.
• W2016674979 hasConcept C2780035454 @default.
• W2016674979 hasConcept C2993143319 @default.
• W2016674979 hasConcept C3013748606 @default.
• W2016674979 hasConcept C501734568 @default.
• W2016674979 hasConcept C54355233 @default.
• W2016674979 hasConcept C76818968 @default.
• W2016674979 hasConcept C86803240 @default.
• W2016674979 hasConcept C98274493 @default.
• W2016674979 hasConceptScore W2016674979C104317684 @default.
• W2016674979 hasConceptScore W2016674979C114851261 @default.
• W2016674979 hasConceptScore W2016674979C125009961 @default.
• W2016674979 hasConceptScore W2016674979C142462285 @default.
• W2016674979 hasConceptScore W2016674979C159047783 @default.
• W2016674979 hasConceptScore W2016674979C2778451633 @default.
• W2016674979 hasConceptScore W2016674979C2780035454 @default.
• W2016674979 hasConceptScore W2016674979C2993143319 @default.
• W2016674979 hasConceptScore W2016674979C3013748606 @default.
• W2016674979 hasConceptScore W2016674979C501734568 @default.
• W2016674979 hasConceptScore W2016674979C54355233 @default.
• W2016674979 hasConceptScore W2016674979C76818968 @default.
• W2016674979 hasConceptScore W2016674979C86803240 @default.
• W2016674979 hasConceptScore W2016674979C98274493 @default.

• next