FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016688375> ?p ?o ?g. }

• W2016688375 abstract "In 1983 Luc Montagnier and his colleagues claimed to have discovered a novel retrovirus presently known as human immunodeficiency virus (HIV). By 1984 HIV was almost universally accepted to be the cause of AIDS. However, 20 years later, HIV cannot account for the phenomena for which the retroviral hypothesis was proposed, namely, Kaposi's sarcoma, decrease in T4 lymphocytes and thus the opportunistic infections in AIDS patients which were assumed to be the direct results of this decrease. Agents other than HIV to which patients belonging to the AIDS risk groups are exposed cause decrease in T4 cells. Neither have the main predictions of the HIV hypothesis been fulfilled. HIV seropositivity in the developed countries still remains restricted to the original high risk groups, no HIV vaccine exists, and no successful animal model has been developed. In this communication, we critically analyse the evidence which in 1983 was claimed to prove the existence of HIV. The phenomena which Montagnier and his colleagues considered proof for the existence of HIV are detection of reverse transcriptase activity; the presence of retrovirus-like particles in the culture; immunological reactivity between proteins from the culture supernatant which, in sucrose density gradients, banded at the density of 1.16 g/ml (purified virus) and antibodies in a patient's (BRU) serum. Reverse transcriptase activity can be found in viruses other than retroviruses and in all normal cells. Reverse transcription can be brought about not only by the enzyme reverse transcriptase but also by normal, cellular DNA polymerases. Retrovirus-like particles are ubiquitous in cultures not infected with retroviruses, especially in conditions employed by Montagnier et al. From the reaction between proteins in the purified virus and antibodies in the patient serum Montagnier concluded that the proteins were HIV proteins and the antibodies were HIV antibodies. Since all antibodies are polyspecific, from such a reaction it is not possible to define the origin of even one reactant let alone both. Even if this were possible, since Montagnier's purified virus did not contain particles with the morphology typical of retroviruses, the proteins cannot be retroviral. We conclude that, these phenomena are non-specific to retroviruses and thus cannot be considered proof for the existence of a unique retrovirus HIV." @default.
• W2016688375 created "2016-06-24" @default.
• W2016688375 creator A5014901270 @default.
• W2016688375 creator A5021905894 @default.
• W2016688375 creator A5024887006 @default.
• W2016688375 creator A5039224486 @default.
• W2016688375 creator A5039506171 @default.
• W2016688375 creator A5053211893 @default.
• W2016688375 creator A5054850627 @default.
• W2016688375 creator A5062371027 @default.
• W2016688375 creator A5072781557 @default.
• W2016688375 creator A5090820768 @default.
• W2016688375 date "2004-01-01" @default.
• W2016688375 modified "2023-09-27" @default.
• W2016688375 title "A critique of the Montagnier evidence for the HIV/AIDS hypothesis" @default.
• W2016688375 cites W141881838 @default.
• W2016688375 cites W1567359448 @default.
• W2016688375 cites W1602910568 @default.
• W2016688375 cites W168778759 @default.
• W2016688375 cites W1893500657 @default.
• W2016688375 cites W1972008542 @default.
• W2016688375 cites W1977282539 @default.
• W2016688375 cites W1977982313 @default.
• W2016688375 cites W1982097469 @default.
• W2016688375 cites W1983867919 @default.
• W2016688375 cites W1990034951 @default.
• W2016688375 cites W1990548708 @default.
• W2016688375 cites W1994533434 @default.
• W2016688375 cites W1998186226 @default.
• W2016688375 cites W2004144408 @default.
• W2016688375 cites W2004351292 @default.
• W2016688375 cites W2027016299 @default.
• W2016688375 cites W2031821446 @default.
• W2016688375 cites W2031845382 @default.
• W2016688375 cites W2034515222 @default.
• W2016688375 cites W2039306418 @default.
• W2016688375 cites W2051028318 @default.
• W2016688375 cites W2054066559 @default.
• W2016688375 cites W2059860936 @default.
• W2016688375 cites W2076952785 @default.
• W2016688375 cites W2089433024 @default.
• W2016688375 cites W2089853912 @default.
• W2016688375 cites W2100424501 @default.
• W2016688375 cites W2100685151 @default.
• W2016688375 cites W2113071805 @default.
• W2016688375 cites W2114128140 @default.
• W2016688375 cites W2131011340 @default.
• W2016688375 cites W2137267461 @default.
• W2016688375 cites W2150437387 @default.
• W2016688375 cites W2161420098 @default.
• W2016688375 cites W2165032352 @default.
• W2016688375 cites W2342933707 @default.
• W2016688375 cites W2397802868 @default.
• W2016688375 cites W2399601586 @default.
• W2016688375 cites W2494867527 @default.
• W2016688375 cites W60005868 @default.
• W2016688375 doi "https://doi.org/10.1016/j.mehy.2004.03.025" @default.
• W2016688375 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15325002" @default.
• W2016688375 hasPublicationYear "2004" @default.
• W2016688375 type Work @default.
• W2016688375 sameAs 2016688375 @default.
• W2016688375 citedByCount "5" @default.
• W2016688375 countsByYear W20166883752016 @default.
• W2016688375 crossrefType "journal-article" @default.
• W2016688375 hasAuthorship W2016688375A5014901270 @default.
• W2016688375 hasAuthorship W2016688375A5021905894 @default.
• W2016688375 hasAuthorship W2016688375A5024887006 @default.
• W2016688375 hasAuthorship W2016688375A5039224486 @default.
• W2016688375 hasAuthorship W2016688375A5039506171 @default.
• W2016688375 hasAuthorship W2016688375A5053211893 @default.
• W2016688375 hasAuthorship W2016688375A5054850627 @default.
• W2016688375 hasAuthorship W2016688375A5062371027 @default.
• W2016688375 hasAuthorship W2016688375A5072781557 @default.
• W2016688375 hasAuthorship W2016688375A5090820768 @default.
• W2016688375 hasConcept C104317684 @default.
• W2016688375 hasConcept C156719811 @default.
• W2016688375 hasConcept C159047783 @default.
• W2016688375 hasConcept C159654299 @default.
• W2016688375 hasConcept C203014093 @default.
• W2016688375 hasConcept C2522874641 @default.
• W2016688375 hasConcept C2778431562 @default.
• W2016688375 hasConcept C2910803801 @default.
• W2016688375 hasConcept C3013748606 @default.
• W2016688375 hasConcept C49105822 @default.
• W2016688375 hasConcept C54355233 @default.
• W2016688375 hasConcept C86803240 @default.
• W2016688375 hasConceptScore W2016688375C104317684 @default.
• W2016688375 hasConceptScore W2016688375C156719811 @default.
• W2016688375 hasConceptScore W2016688375C159047783 @default.
• W2016688375 hasConceptScore W2016688375C159654299 @default.
• W2016688375 hasConceptScore W2016688375C203014093 @default.
• W2016688375 hasConceptScore W2016688375C2522874641 @default.
• W2016688375 hasConceptScore W2016688375C2778431562 @default.
• W2016688375 hasConceptScore W2016688375C2910803801 @default.
• W2016688375 hasConceptScore W2016688375C3013748606 @default.
• W2016688375 hasConceptScore W2016688375C49105822 @default.
• W2016688375 hasConceptScore W2016688375C54355233 @default.
• W2016688375 hasConceptScore W2016688375C86803240 @default.
• W2016688375 hasLocation W20166883751 @default.
• W2016688375 hasLocation W20166883752 @default.

• next