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- W2016704490 endingPage "4560" @default.
- W2016704490 startingPage "4553" @default.
- W2016704490 abstract "Abstract Reclassification of Hodgkin disease as Hodgkin lymphoma (HL) represents a milestone in the lymphoma field, awarding recent insights in the molecular biology of Hodgkin and Reed-Sternberg (H-RS) cells and their environment. This review summarizes antiapoptotic and proproliferative pathways involved in the pathogenesis of this disease with the ultimate goal of translating laboratory knowledge into clinical decision making. The focus is on potential targets and novel drugs, which are discussed in the context of the complex biology of HL. Considering that HL patients are more likely to die from acute and late treatment-related toxicities than from HL itself, the introduction of targeted, biologically based therapies for HL patients with palliative and eventually curative intention might be justified. (Blood. 2005;105:4553-4560)" @default.
- W2016704490 created "2016-06-24" @default.
- W2016704490 creator A5003056562 @default.
- W2016704490 creator A5058511375 @default.
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- W2016704490 date "2005-06-15" @default.
- W2016704490 modified "2023-10-17" @default.
- W2016704490 title "From Hodgkin disease to Hodgkin lymphoma: biologic insights and therapeutic potential" @default.
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