FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016709429> ?p ?o ?g. }

• W2016709429 endingPage "1067" @default.
• W2016709429 startingPage "1052" @default.
• W2016709429 abstract "Previous studies have attempted to confirm the association between the ABCB1-C3435T polymorphism and drug-resistant epilepsy and produced discordant findings. A meta-analysis was conducted to assess the role of the C3435T polymorphism in drug-resistance in epilepsy. Databases were obtained from PubMed, Embase, the Chinese Wanfang, CNKI, and Chongqing VIP database, and all relevant studies were compiled up to February 2013. Odds ratios (ORs) were calculated using models of both fixed- and random-effects for comparisons of alleles and genotypes. Subgroup meta-analyses were carried out based on epilepsy subtype, age, therapeutic regimen, definition of drug-responsiveness and drug-resistance using alleles and genotypes models. Publication bias was tested by Begg's test and inverted funnel plot, and heterogeneity was checked by Cochran's Q statistic and the inconsistency index (I2). Cumulative meta-analyses were adopted to test the robustness of the findings. A total of 38 association studies including a total of 8716 subjects, 4037 drug-resistant patients and 4679 drug-responsive epilepsy patients were pooled in this meta-analysis. The association of ABCB1-C3435T with risk of drug-resistance was significant in the overall population (T allele vs. C allele, OR: 1.21; 95%CI: 1.06-1.39; P=0.006) and in Caucasians, adults, groups treated with various drugs, a '>10 seizures in a year' group based on resistance and a '≥2 years seizure free' group based on response subgroup analysis. The ABCB1-C3435T polymorphism is likely to act as a risk factor for resistance to antiepileptic drugs that needs to be confirmed through further studies." @default.
• W2016709429 created "2016-06-24" @default.
• W2016709429 creator A5004019336 @default.
• W2016709429 creator A5004254530 @default.
• W2016709429 creator A5011877960 @default.
• W2016709429 creator A5016797934 @default.
• W2016709429 creator A5020779993 @default.
• W2016709429 creator A5022683477 @default.
• W2016709429 creator A5022894892 @default.
• W2016709429 creator A5026540420 @default.
• W2016709429 creator A5048411184 @default.
• W2016709429 creator A5065570486 @default.
• W2016709429 creator A5071634770 @default.
• W2016709429 creator A5079910380 @default.
• W2016709429 creator A5089890518 @default.
• W2016709429 creator A5091158220 @default.
• W2016709429 date "2014-08-01" @default.
• W2016709429 modified "2023-09-30" @default.
• W2016709429 title "The ABCB1-C3435T polymorphism likely acts as a risk factor for resistance to antiepileptic drugs" @default.
• W2016709429 cites W1731775399 @default.
• W2016709429 cites W1939410246 @default.
• W2016709429 cites W1956099131 @default.
• W2016709429 cites W1958692533 @default.
• W2016709429 cites W1967287259 @default.
• W2016709429 cites W1967913742 @default.
• W2016709429 cites W1975445668 @default.
• W2016709429 cites W1976879156 @default.
• W2016709429 cites W1979324912 @default.
• W2016709429 cites W1983678363 @default.
• W2016709429 cites W1985531753 @default.
• W2016709429 cites W1986239798 @default.
• W2016709429 cites W1991205228 @default.
• W2016709429 cites W1994572997 @default.
• W2016709429 cites W1998742400 @default.
• W2016709429 cites W2000605006 @default.
• W2016709429 cites W2003612592 @default.
• W2016709429 cites W2013533336 @default.
• W2016709429 cites W2023544660 @default.
• W2016709429 cites W2029351291 @default.
• W2016709429 cites W2030449842 @default.
• W2016709429 cites W2032417894 @default.
• W2016709429 cites W2033992621 @default.
• W2016709429 cites W2034204487 @default.
• W2016709429 cites W2044199354 @default.
• W2016709429 cites W2051229292 @default.
• W2016709429 cites W2053616305 @default.
• W2016709429 cites W2054216255 @default.
• W2016709429 cites W2055412274 @default.
• W2016709429 cites W2061230148 @default.
• W2016709429 cites W2061928059 @default.
• W2016709429 cites W2063288921 @default.
• W2016709429 cites W2069118421 @default.
• W2016709429 cites W2075399115 @default.
• W2016709429 cites W2081281742 @default.
• W2016709429 cites W2082604108 @default.
• W2016709429 cites W2082885545 @default.
• W2016709429 cites W2089164698 @default.
• W2016709429 cites W2093176036 @default.
• W2016709429 cites W2101061157 @default.
• W2016709429 cites W2107373964 @default.
• W2016709429 cites W2110526135 @default.
• W2016709429 cites W2110886272 @default.
• W2016709429 cites W2111814093 @default.
• W2016709429 cites W2115316843 @default.
• W2016709429 cites W2118342649 @default.
• W2016709429 cites W2123347744 @default.
• W2016709429 cites W2131815155 @default.
• W2016709429 cites W2135116638 @default.
• W2016709429 cites W2138066381 @default.
• W2016709429 cites W2140569148 @default.
• W2016709429 cites W2141356899 @default.
• W2016709429 cites W2157480615 @default.
• W2016709429 cites W2157823046 @default.
• W2016709429 cites W2161208527 @default.
• W2016709429 cites W2164261965 @default.
• W2016709429 cites W2168578192 @default.
• W2016709429 cites W2169006271 @default.
• W2016709429 cites W2171574374 @default.
• W2016709429 cites W2330149118 @default.
• W2016709429 cites W4211013529 @default.
• W2016709429 doi "https://doi.org/10.1016/j.eplepsyres.2014.03.019" @default.
• W2016709429 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24794827" @default.
• W2016709429 hasPublicationYear "2014" @default.
• W2016709429 type Work @default.
• W2016709429 sameAs 2016709429 @default.
• W2016709429 citedByCount "16" @default.
• W2016709429 countsByYear W20167094292014 @default.
• W2016709429 countsByYear W20167094292015 @default.
• W2016709429 countsByYear W20167094292016 @default.
• W2016709429 countsByYear W20167094292017 @default.
• W2016709429 countsByYear W20167094292018 @default.
• W2016709429 countsByYear W20167094292021 @default.
• W2016709429 countsByYear W20167094292023 @default.
• W2016709429 crossrefType "journal-article" @default.
• W2016709429 hasAuthorship W2016709429A5004019336 @default.
• W2016709429 hasAuthorship W2016709429A5004254530 @default.
• W2016709429 hasAuthorship W2016709429A5011877960 @default.
• W2016709429 hasAuthorship W2016709429A5016797934 @default.

• next