Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016751408> ?p ?o ?g. }
- W2016751408 endingPage "392" @default.
- W2016751408 startingPage "387" @default.
- W2016751408 abstract "Seven healthy patients were investigated during midazolam-fentanyl nitrous oxide-oxygen anaesthesia. The mechanical twitch response of the adductor pollicis muscle was recorded simultaneously during bilateral supramaximal train-of-four (TOF) stimulation of the ulnar nerves at the wrist. Intense neuromuscular block was evaluated using the post-tetanic count (PTC) method. Core temperature and the peripheral skin temperature of one arm were kept normal and stable. Following cooling of the other arm to a peripheral hand skin temperature of 27d̀C, vecuronium was administered in a bolus dose of 0.05 mg-kg-1 followed by maintenance doses of 0.02 mg-kg-1. In the hypothermic and the normothermic arm the onset time following the bolus dose was 180 ± 40 (mean ± s.d.) seconds and 140 ± 30 s, respectively, the duration of action was 26.4 ± 4.5 and 16.5 ± 4.0 min and the recovery time was 265 ± 90 and 130±60 s (P<0.01). The time course of action following maintenance doses showed a similar marked difference between the hypothermic and the normothermic arm. In the normothermic arm a close correlation was found between the number of posttetanic twitches and the time to first response to TOF stimulation. In contrast, in the hypothermic arm the number of post-tetanic twitches showed great variation with a poor correlation to the duration of intense neuromuscular block. It is concluded that the time course of action of a vecuronium-induced neuromuscular block is markedly prolonged during peripheral hypothermia and intense neuromuscular block cannot reliably be assessed using the PTC method at low peripheral temperature. Normal core and peripheral temperature is essential for correct evaluation of a neuromuscular block." @default.
- W2016751408 created "2016-06-24" @default.
- W2016751408 creator A5015602415 @default.
- W2016751408 creator A5018679545 @default.
- W2016751408 creator A5068029374 @default.
- W2016751408 date "1991-07-01" @default.
- W2016751408 modified "2023-09-24" @default.
- W2016751408 title "The effect of peripheral hypothermia on a vecuronium-induced neuromuscular block" @default.
- W2016751408 cites W1967862485 @default.
- W2016751408 cites W1996651439 @default.
- W2016751408 cites W2038442286 @default.
- W2016751408 cites W2039001380 @default.
- W2016751408 cites W2058874590 @default.
- W2016751408 cites W2092594729 @default.
- W2016751408 cites W2110755333 @default.
- W2016751408 cites W2132516036 @default.
- W2016751408 cites W2135787460 @default.
- W2016751408 cites W2152709118 @default.
- W2016751408 cites W2155437817 @default.
- W2016751408 cites W4230404970 @default.
- W2016751408 cites W4323874587 @default.
- W2016751408 doi "https://doi.org/10.1111/j.1399-6576.1991.tb03315.x" @default.
- W2016751408 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1679593" @default.
- W2016751408 hasPublicationYear "1991" @default.
- W2016751408 type Work @default.
- W2016751408 sameAs 2016751408 @default.
- W2016751408 citedByCount "46" @default.
- W2016751408 countsByYear W20167514082015 @default.
- W2016751408 countsByYear W20167514082016 @default.
- W2016751408 countsByYear W20167514082017 @default.
- W2016751408 countsByYear W20167514082019 @default.
- W2016751408 countsByYear W20167514082020 @default.
- W2016751408 countsByYear W20167514082022 @default.
- W2016751408 crossrefType "journal-article" @default.
- W2016751408 hasAuthorship W2016751408A5015602415 @default.
- W2016751408 hasAuthorship W2016751408A5018679545 @default.
- W2016751408 hasAuthorship W2016751408A5068029374 @default.
- W2016751408 hasConcept C126322002 @default.
- W2016751408 hasConcept C141071460 @default.
- W2016751408 hasConcept C170493617 @default.
- W2016751408 hasConcept C206044474 @default.
- W2016751408 hasConcept C25274449 @default.
- W2016751408 hasConcept C2776184885 @default.
- W2016751408 hasConcept C2776814716 @default.
- W2016751408 hasConcept C2777390192 @default.
- W2016751408 hasConcept C2778000748 @default.
- W2016751408 hasConcept C2778216619 @default.
- W2016751408 hasConcept C2778931672 @default.
- W2016751408 hasConcept C2779940140 @default.
- W2016751408 hasConcept C2781072394 @default.
- W2016751408 hasConcept C2781184374 @default.
- W2016751408 hasConcept C2909465803 @default.
- W2016751408 hasConcept C3020341438 @default.
- W2016751408 hasConcept C42219234 @default.
- W2016751408 hasConcept C43376680 @default.
- W2016751408 hasConcept C46762472 @default.
- W2016751408 hasConcept C6742658 @default.
- W2016751408 hasConcept C71924100 @default.
- W2016751408 hasConceptScore W2016751408C126322002 @default.
- W2016751408 hasConceptScore W2016751408C141071460 @default.
- W2016751408 hasConceptScore W2016751408C170493617 @default.
- W2016751408 hasConceptScore W2016751408C206044474 @default.
- W2016751408 hasConceptScore W2016751408C25274449 @default.
- W2016751408 hasConceptScore W2016751408C2776184885 @default.
- W2016751408 hasConceptScore W2016751408C2776814716 @default.
- W2016751408 hasConceptScore W2016751408C2777390192 @default.
- W2016751408 hasConceptScore W2016751408C2778000748 @default.
- W2016751408 hasConceptScore W2016751408C2778216619 @default.
- W2016751408 hasConceptScore W2016751408C2778931672 @default.
- W2016751408 hasConceptScore W2016751408C2779940140 @default.
- W2016751408 hasConceptScore W2016751408C2781072394 @default.
- W2016751408 hasConceptScore W2016751408C2781184374 @default.
- W2016751408 hasConceptScore W2016751408C2909465803 @default.
- W2016751408 hasConceptScore W2016751408C3020341438 @default.
- W2016751408 hasConceptScore W2016751408C42219234 @default.
- W2016751408 hasConceptScore W2016751408C43376680 @default.
- W2016751408 hasConceptScore W2016751408C46762472 @default.
- W2016751408 hasConceptScore W2016751408C6742658 @default.
- W2016751408 hasConceptScore W2016751408C71924100 @default.
- W2016751408 hasIssue "5" @default.
- W2016751408 hasLocation W20167514081 @default.
- W2016751408 hasLocation W20167514082 @default.
- W2016751408 hasOpenAccess W2016751408 @default.
- W2016751408 hasPrimaryLocation W20167514081 @default.
- W2016751408 hasRelatedWork W1491336070 @default.
- W2016751408 hasRelatedWork W1965407822 @default.
- W2016751408 hasRelatedWork W2016751408 @default.
- W2016751408 hasRelatedWork W2063306954 @default.
- W2016751408 hasRelatedWork W2111639991 @default.
- W2016751408 hasRelatedWork W2123010226 @default.
- W2016751408 hasRelatedWork W2155326302 @default.
- W2016751408 hasRelatedWork W2356897053 @default.
- W2016751408 hasRelatedWork W2411762494 @default.
- W2016751408 hasRelatedWork W2419292807 @default.
- W2016751408 hasVolume "35" @default.
- W2016751408 isParatext "false" @default.
- W2016751408 isRetracted "false" @default.
- W2016751408 magId "2016751408" @default.