Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016760713> ?p ?o ?g. }
- W2016760713 endingPage "1421" @default.
- W2016760713 startingPage "1416" @default.
- W2016760713 abstract "Helicobacter (H.) suis colonizes the stomach of more than 60% of slaughter pigs and is also of zoonotic importance. Recently, this bacterium was isolated in vitro, enabling the use of pure cultures for research purposes. In this study, mice were immunized intranasally or subcutaneously with whole bacterial cell lysate of H. suis or the closely related species H. bizzozeronii and H. cynogastricus, and subsequently challenged with H. suis. Control groups consisted of non-immunized and non-challenged mice (negative control group), as well as of sham-immunized mice that were inoculated with H. suis (positive control group). Urease tests on stomach tissue samples at 7 weeks after challenge infection were negative in all negative control mice, all intranasally immunized mice except one, and in all and 3 out of 5 animals of the H. cynogastricus and H. suis subcutaneously immunized groups, respectively. H. suis DNA was detected by PCR in the stomach of all positive control animals and all subcutaneously immunized/challenged animals. All negative control animals and some intranasally immunized/challenged mice were PCR-negative. In conclusion, immunization using antigens derived from the same or closely related bacterial species suppressed gastric colonization with H. suis, but complete protection was only achieved in a minority of animals following intranasal immunization." @default.
- W2016760713 created "2016-06-24" @default.
- W2016760713 creator A5022762999 @default.
- W2016760713 creator A5031299412 @default.
- W2016760713 creator A5044653645 @default.
- W2016760713 creator A5052738405 @default.
- W2016760713 creator A5054586160 @default.
- W2016760713 creator A5074079751 @default.
- W2016760713 creator A5077557975 @default.
- W2016760713 creator A5079195611 @default.
- W2016760713 creator A5087164752 @default.
- W2016760713 date "2009-02-01" @default.
- W2016760713 modified "2023-10-16" @default.
- W2016760713 title "Protective immunization with homologous and heterologous antigens against Helicobacter suis challenge in a mouse model" @default.
- W2016760713 cites W1775749144 @default.
- W2016760713 cites W1865891605 @default.
- W2016760713 cites W1938059351 @default.
- W2016760713 cites W1940581443 @default.
- W2016760713 cites W1970532044 @default.
- W2016760713 cites W1980239790 @default.
- W2016760713 cites W1980364181 @default.
- W2016760713 cites W1982352399 @default.
- W2016760713 cites W1993801215 @default.
- W2016760713 cites W2004166130 @default.
- W2016760713 cites W200837969 @default.
- W2016760713 cites W2009346366 @default.
- W2016760713 cites W2015323822 @default.
- W2016760713 cites W2015817879 @default.
- W2016760713 cites W2022316126 @default.
- W2016760713 cites W2023466305 @default.
- W2016760713 cites W2032961162 @default.
- W2016760713 cites W2034999697 @default.
- W2016760713 cites W2035654452 @default.
- W2016760713 cites W2042577423 @default.
- W2016760713 cites W2044255471 @default.
- W2016760713 cites W2044499333 @default.
- W2016760713 cites W2051442383 @default.
- W2016760713 cites W2061938579 @default.
- W2016760713 cites W2064748217 @default.
- W2016760713 cites W2068206522 @default.
- W2016760713 cites W2083918026 @default.
- W2016760713 cites W2095253757 @default.
- W2016760713 cites W2101730203 @default.
- W2016760713 cites W2102056982 @default.
- W2016760713 cites W2114701070 @default.
- W2016760713 cites W2116391007 @default.
- W2016760713 cites W2116640476 @default.
- W2016760713 cites W2118986185 @default.
- W2016760713 cites W2119541191 @default.
- W2016760713 cites W2120227373 @default.
- W2016760713 cites W2122086704 @default.
- W2016760713 cites W2124994169 @default.
- W2016760713 cites W2130393448 @default.
- W2016760713 cites W2143107875 @default.
- W2016760713 cites W2143140859 @default.
- W2016760713 cites W2143818958 @default.
- W2016760713 cites W2144885426 @default.
- W2016760713 cites W2150636954 @default.
- W2016760713 cites W2152000612 @default.
- W2016760713 cites W2155154252 @default.
- W2016760713 cites W2162087017 @default.
- W2016760713 cites W2162400276 @default.
- W2016760713 cites W2168355176 @default.
- W2016760713 cites W2170854088 @default.
- W2016760713 cites W2402055246 @default.
- W2016760713 cites W4211017205 @default.
- W2016760713 doi "https://doi.org/10.1016/j.vaccine.2008.12.031" @default.
- W2016760713 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19136039" @default.
- W2016760713 hasPublicationYear "2009" @default.
- W2016760713 type Work @default.
- W2016760713 sameAs 2016760713 @default.
- W2016760713 citedByCount "9" @default.
- W2016760713 countsByYear W20167607132012 @default.
- W2016760713 countsByYear W20167607132013 @default.
- W2016760713 countsByYear W20167607132015 @default.
- W2016760713 countsByYear W20167607132022 @default.
- W2016760713 crossrefType "journal-article" @default.
- W2016760713 hasAuthorship W2016760713A5022762999 @default.
- W2016760713 hasAuthorship W2016760713A5031299412 @default.
- W2016760713 hasAuthorship W2016760713A5044653645 @default.
- W2016760713 hasAuthorship W2016760713A5052738405 @default.
- W2016760713 hasAuthorship W2016760713A5054586160 @default.
- W2016760713 hasAuthorship W2016760713A5074079751 @default.
- W2016760713 hasAuthorship W2016760713A5077557975 @default.
- W2016760713 hasAuthorship W2016760713A5079195611 @default.
- W2016760713 hasAuthorship W2016760713A5087164752 @default.
- W2016760713 hasConcept C104317684 @default.
- W2016760713 hasConcept C147483822 @default.
- W2016760713 hasConcept C159047783 @default.
- W2016760713 hasConcept C203014093 @default.
- W2016760713 hasConcept C2775976552 @default.
- W2016760713 hasConcept C2776409635 @default.
- W2016760713 hasConcept C2780115692 @default.
- W2016760713 hasConcept C2780801004 @default.
- W2016760713 hasConcept C2780832600 @default.
- W2016760713 hasConcept C54355233 @default.
- W2016760713 hasConcept C55493867 @default.
- W2016760713 hasConcept C60987743 @default.