FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016771776> ?p ?o ?g. }

• W2016771776 endingPage "191" @default.
• W2016771776 startingPage "181" @default.
• W2016771776 abstract "Tropomyosins are a family of actin-binding proteins with diverse roles in actin filament function. One of the best characterized roles is the regulation of muscle contraction. Tropomyosin isoforms can be generated from different genes, and from alternative promoters and alternative splicing from the same gene. In this work, we have isolated sequences for tropomyosin isoforms from the cestode Mesocestoides corti, and searched for tropomyosin genes and isoforms in other flatworms. Two genes are conserved in the cestodes M. corti and Echinococcus multilocularis, and in the trematode Schistosoma mansoni. Both genes have the same structure, and each gene gives rise to at least two different isoforms, a high molecular weight (HMW) and a low molecular weight (LMW) one. Because most exons are duplicated and spliced in a mutually exclusive fashion, isoforms from one gene only share one exon and are highly divergent. The gene duplication preceded the divergence of neodermatans and the planarian Schmidtea mediterranea. Further duplications occurred in Schmidtea, coupled to the selective loss of duplicated exons, resulting in genes that only code for HMW or LMW isoforms. A polyclonal antibody raised against a HMW tropomyosin from Echinococcus granulosus was demonstrated to specifically recognize HMW tropomyosin isoforms of M. corti, and used to study their expression during segmentation. HMW tropomyosins are expressed in muscle layers, with very low or absent levels in other tissues. No expression of HMW tropomyosins is present in early or late genital primordia, and expression only begins once muscle fibers develop in the genital ducts. Therefore, HMW tropomyosins are markers for the development of muscles during the final differentiation of genital primordia." @default.
• W2016771776 created "2016-06-24" @default.
• W2016771776 creator A5007656292 @default.
• W2016771776 creator A5024710851 @default.
• W2016771776 creator A5028113102 @default.
• W2016771776 creator A5030778973 @default.
• W2016771776 creator A5030932928 @default.
• W2016771776 creator A5042340577 @default.
• W2016771776 creator A5075811180 @default.
• W2016771776 date "2011-02-01" @default.
• W2016771776 modified "2023-10-17" @default.
• W2016771776 title "Developmental expression of high molecular weight tropomyosin isoforms in Mesocestoides corti" @default.
• W2016771776 cites W101110345 @default.
• W2016771776 cites W119573302 @default.
• W2016771776 cites W131138613 @default.
• W2016771776 cites W1539899651 @default.
• W2016771776 cites W1933545887 @default.
• W2016771776 cites W1963480416 @default.
• W2016771776 cites W1968317127 @default.
• W2016771776 cites W1973956189 @default.
• W2016771776 cites W1987361448 @default.
• W2016771776 cites W2003775374 @default.
• W2016771776 cites W2004036624 @default.
• W2016771776 cites W2006037896 @default.
• W2016771776 cites W2017550303 @default.
• W2016771776 cites W2018373528 @default.
• W2016771776 cites W2044615114 @default.
• W2016771776 cites W2052781326 @default.
• W2016771776 cites W2055652979 @default.
• W2016771776 cites W2058889208 @default.
• W2016771776 cites W2059462822 @default.
• W2016771776 cites W2063216803 @default.
• W2016771776 cites W2074285965 @default.
• W2016771776 cites W2094169801 @default.
• W2016771776 cites W2098872898 @default.
• W2016771776 cites W2109577572 @default.
• W2016771776 cites W2111984642 @default.
• W2016771776 cites W2128845826 @default.
• W2016771776 cites W2146058063 @default.
• W2016771776 cites W2148848167 @default.
• W2016771776 cites W2160012716 @default.
• W2016771776 cites W2162225623 @default.
• W2016771776 cites W2164590764 @default.
• W2016771776 cites W2229559736 @default.
• W2016771776 cites W2323498682 @default.
• W2016771776 cites W2326148980 @default.
• W2016771776 cites W4211177544 @default.
• W2016771776 cites W6358938 @default.
• W2016771776 cites W77122809 @default.
• W2016771776 doi "https://doi.org/10.1016/j.molbiopara.2010.11.009" @default.
• W2016771776 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21093500" @default.
• W2016771776 hasPublicationYear "2011" @default.
• W2016771776 type Work @default.
• W2016771776 sameAs 2016771776 @default.
• W2016771776 citedByCount "18" @default.
• W2016771776 countsByYear W20167717762012 @default.
• W2016771776 countsByYear W20167717762013 @default.
• W2016771776 countsByYear W20167717762014 @default.
• W2016771776 countsByYear W20167717762015 @default.
• W2016771776 countsByYear W20167717762016 @default.
• W2016771776 countsByYear W20167717762017 @default.
• W2016771776 countsByYear W20167717762018 @default.
• W2016771776 countsByYear W20167717762019 @default.
• W2016771776 countsByYear W20167717762020 @default.
• W2016771776 countsByYear W20167717762021 @default.
• W2016771776 countsByYear W20167717762022 @default.
• W2016771776 countsByYear W20167717762023 @default.
• W2016771776 crossrefType "journal-article" @default.
• W2016771776 hasAuthorship W2016771776A5007656292 @default.
• W2016771776 hasAuthorship W2016771776A5024710851 @default.
• W2016771776 hasAuthorship W2016771776A5028113102 @default.
• W2016771776 hasAuthorship W2016771776A5030778973 @default.
• W2016771776 hasAuthorship W2016771776A5030932928 @default.
• W2016771776 hasAuthorship W2016771776A5042340577 @default.
• W2016771776 hasAuthorship W2016771776A5075811180 @default.
• W2016771776 hasConcept C104317684 @default.
• W2016771776 hasConcept C125705527 @default.
• W2016771776 hasConcept C150194340 @default.
• W2016771776 hasConcept C153911025 @default.
• W2016771776 hasConcept C205875245 @default.
• W2016771776 hasConcept C2779922708 @default.
• W2016771776 hasConcept C36823959 @default.
• W2016771776 hasConcept C53345823 @default.
• W2016771776 hasConcept C54355233 @default.
• W2016771776 hasConcept C5911399 @default.
• W2016771776 hasConcept C7602840 @default.
• W2016771776 hasConcept C86803240 @default.
• W2016771776 hasConcept C95444343 @default.
• W2016771776 hasConceptScore W2016771776C104317684 @default.
• W2016771776 hasConceptScore W2016771776C125705527 @default.
• W2016771776 hasConceptScore W2016771776C150194340 @default.
• W2016771776 hasConceptScore W2016771776C153911025 @default.
• W2016771776 hasConceptScore W2016771776C205875245 @default.
• W2016771776 hasConceptScore W2016771776C2779922708 @default.
• W2016771776 hasConceptScore W2016771776C36823959 @default.
• W2016771776 hasConceptScore W2016771776C53345823 @default.
• W2016771776 hasConceptScore W2016771776C54355233 @default.
• W2016771776 hasConceptScore W2016771776C5911399 @default.

• next