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- W2016772384 abstract "Recent work published by this laboratory in the subhuman primate has demonstrated that the primary cause of the decrease in mean systemic arterial pressure following a lethal injection of endotoxin is a decrease in venous return. 1 However, a marked difference in response to endotoxin is observed in monkeys in contrast to dogs. In the former, a gradual fall in mean systemic arterial pressure is observed, and there is neither demonstrable pooling in the hepatosplanchnic bed nor loss of circulating blood to extravascular compartments. 1-5 The cause of the decrease in venous return in the primate has not been determined. A previous study did not differentiate between a decrease in venous return due to peripheral pooling or failure of cardiac contractility. 1 The cardiac output in some human patients shows a steady decline, 6,7 although there is no evidence of primary cardiac failure in man 6 or the nonhuman primate." @default.
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- W2016772384 date "1970-05-01" @default.
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- W2016772384 title "Mechanism of Decreased Venous Return" @default.
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- W2016772384 doi "https://doi.org/10.1001/archsurg.1970.01340230066017" @default.
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