Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016782014> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2016782014 endingPage "36" @default.
- W2016782014 startingPage "30" @default.
- W2016782014 abstract "Objective Breast cancer is one of the principal oncological challenges in the Western world. Currently, there are only a few reliable predictive methods for monitoring treatment. We investigated the ability of carbon-11 methionine (11C-MET) positron emission tomography (PET) to evaluate early response to therapy in advanced breast cancer. Methods Thirteen patients with metastases in the lungs/pleura, lymph nodes, soft tissue, or bones entered a MET PET study both before and after the first cycle of polychemotherapy (n=4), or after the first month of therapy with hormones (n=5), or low dose weekly cytostatics (n=3). One patient underwent three PET studies: before hormonal therapy, after 1 month of hormonal therapy, and after the first cycle of polychemotherapy (total, 27 studies). MET accumulation in the metastatic sites was measured as standardized uptake values (SUVs), and the pretreatment and post-treatment SUVs were compared with each other and the clinical follow-up data. Results A total of 26 different metastatic sites were investigated in 13 patients. All metastases were visible by MET PET except one superficially spreading local skin recurrence, probably because of respiratory movements. Five new metastatic sites were detected. After therapy the SUVs decreased significantly (30–54%; P<0.05) in all six responding metastatic sites, whereas the SUVs of nonresponding metastases decreased somewhat (11–13%; n=4), remained stable (±8%; n=10), or increased (13–23%; n=4) (P=NS). The SUVs of two nonresponding metastatic sites decreased clearly. Physiological MET uptake in the salivary glands, the myocardium, and the bone marrow did not disturb the image interpretation. Conclusion MET PET may be useful in assessing the early response to therapy in advanced breast cancer." @default.
- W2016782014 created "2016-06-24" @default.
- W2016782014 creator A5030162855 @default.
- W2016782014 creator A5059466134 @default.
- W2016782014 creator A5067820500 @default.
- W2016782014 creator A5068238733 @default.
- W2016782014 creator A5089814370 @default.
- W2016782014 creator A5090418139 @default.
- W2016782014 date "2009-01-01" @default.
- W2016782014 modified "2023-10-18" @default.
- W2016782014 title "Preliminary study of carbon-11 methionine PET in the evaluation of early response to therapy in advanced breast cancer" @default.
- W2016782014 cites W1762109430 @default.
- W2016782014 cites W1906753921 @default.
- W2016782014 cites W1955188776 @default.
- W2016782014 cites W1984079023 @default.
- W2016782014 cites W2031477339 @default.
- W2016782014 cites W2038310765 @default.
- W2016782014 cites W2055572483 @default.
- W2016782014 cites W2062293270 @default.
- W2016782014 cites W2067543017 @default.
- W2016782014 cites W2107277934 @default.
- W2016782014 cites W2108549165 @default.
- W2016782014 cites W2139248078 @default.
- W2016782014 cites W2140824213 @default.
- W2016782014 cites W2146478870 @default.
- W2016782014 cites W2177221443 @default.
- W2016782014 cites W2225412566 @default.
- W2016782014 doi "https://doi.org/10.1097/mnm.0b013e328313b7bc" @default.
- W2016782014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19306512" @default.
- W2016782014 hasPublicationYear "2009" @default.
- W2016782014 type Work @default.
- W2016782014 sameAs 2016782014 @default.
- W2016782014 citedByCount "41" @default.
- W2016782014 countsByYear W20167820142012 @default.
- W2016782014 countsByYear W20167820142013 @default.
- W2016782014 countsByYear W20167820142014 @default.
- W2016782014 countsByYear W20167820142015 @default.
- W2016782014 countsByYear W20167820142016 @default.
- W2016782014 countsByYear W20167820142017 @default.
- W2016782014 countsByYear W20167820142018 @default.
- W2016782014 countsByYear W20167820142019 @default.
- W2016782014 countsByYear W20167820142021 @default.
- W2016782014 countsByYear W20167820142022 @default.
- W2016782014 countsByYear W20167820142023 @default.
- W2016782014 crossrefType "journal-article" @default.
- W2016782014 hasAuthorship W2016782014A5030162855 @default.
- W2016782014 hasAuthorship W2016782014A5059466134 @default.
- W2016782014 hasAuthorship W2016782014A5067820500 @default.
- W2016782014 hasAuthorship W2016782014A5068238733 @default.
- W2016782014 hasAuthorship W2016782014A5089814370 @default.
- W2016782014 hasAuthorship W2016782014A5090418139 @default.
- W2016782014 hasConcept C121608353 @default.
- W2016782014 hasConcept C126322002 @default.
- W2016782014 hasConcept C126838900 @default.
- W2016782014 hasConcept C143998085 @default.
- W2016782014 hasConcept C2775842073 @default.
- W2016782014 hasConcept C2775930923 @default.
- W2016782014 hasConcept C2778311097 @default.
- W2016782014 hasConcept C2780275930 @default.
- W2016782014 hasConcept C2989005 @default.
- W2016782014 hasConcept C530470458 @default.
- W2016782014 hasConcept C71315377 @default.
- W2016782014 hasConcept C71924100 @default.
- W2016782014 hasConceptScore W2016782014C121608353 @default.
- W2016782014 hasConceptScore W2016782014C126322002 @default.
- W2016782014 hasConceptScore W2016782014C126838900 @default.
- W2016782014 hasConceptScore W2016782014C143998085 @default.
- W2016782014 hasConceptScore W2016782014C2775842073 @default.
- W2016782014 hasConceptScore W2016782014C2775930923 @default.
- W2016782014 hasConceptScore W2016782014C2778311097 @default.
- W2016782014 hasConceptScore W2016782014C2780275930 @default.
- W2016782014 hasConceptScore W2016782014C2989005 @default.
- W2016782014 hasConceptScore W2016782014C530470458 @default.
- W2016782014 hasConceptScore W2016782014C71315377 @default.
- W2016782014 hasConceptScore W2016782014C71924100 @default.
- W2016782014 hasIssue "1" @default.
- W2016782014 hasLocation W20167820141 @default.
- W2016782014 hasLocation W20167820142 @default.
- W2016782014 hasOpenAccess W2016782014 @default.
- W2016782014 hasPrimaryLocation W20167820141 @default.
- W2016782014 hasRelatedWork W1970735557 @default.
- W2016782014 hasRelatedWork W1988462970 @default.
- W2016782014 hasRelatedWork W2006323479 @default.
- W2016782014 hasRelatedWork W2026963896 @default.
- W2016782014 hasRelatedWork W2106576262 @default.
- W2016782014 hasRelatedWork W2224319365 @default.
- W2016782014 hasRelatedWork W2603750384 @default.
- W2016782014 hasRelatedWork W3091780641 @default.
- W2016782014 hasRelatedWork W3181412252 @default.
- W2016782014 hasRelatedWork W4285804722 @default.
- W2016782014 hasVolume "30" @default.
- W2016782014 isParatext "false" @default.
- W2016782014 isRetracted "false" @default.
- W2016782014 magId "2016782014" @default.
- W2016782014 workType "article" @default.