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- W2016784562 abstract "The incorporation of de-[2-14C]cytidine or de-[2-14C]CMP into the thymine and cytosine of chick-embryo DNA occurs at a ratio of almost 2:1, which is the converse of results previously reported for [2-14C]cytidine. de-Thymidine stimulated the incorporation of de-[2-14C]cytidine into the de-cytidine of DNA by 40–50%. This effect appears related to the conversion of de-thymidine to de-thymidie triphosphate, which is an effective inhibitor of both deoxycytidylate deaminase and deoxyuridine kinase. The inhibition of these enzymes would have the effect of making decytidine more available as a precursor of DNA de-cytidine. N-methyl and N,N-dimethyl-de-cytidine stimulated the incorporation of de-[2-14C]cytidine into both DNA de-thymidine and de-cytidine." @default.
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- W2016784562 date "1963-01-01" @default.
- W2016784562 modified "2023-09-24" @default.
- W2016784562 title "Nucleotide interconversions VIII. Thymidine-sparing effect on the utilization of de-cytidine by chick-embryo mince" @default.
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- W2016784562 doi "https://doi.org/10.1016/0926-6550(63)90441-9" @default.
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