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- W2016788601 abstract "Abstract The route and the rate of the intestinal absorption of [1- 14 C]oleic, [1- 14 C]-caprylic, and 2-[ 14 C]ethyl- n -caproic acids have been studied using lymph- and portal vein-cannulated rats. It was found that 85% of absorbed oleic acid was transported via lymphatic system. However, as much as 15% of absorbed oleic acid was transported directly via the portal system. With short-chain fatty acids, between 94–98% of the absorbed acids were transported via the portal system. Studies on the rate of the intestinal absorption of these acids indicated that 2-ethyl- n -caproic acid was absorbed less completely and subsequently metabolized less effectively than the corresponding straight-chain fatty acid, caprylic acid. Studies on the distribution of radioactivity in lymph lipids showed that most of the radioactivity (85%) was present as triglycerides when [ 14 C]oleic acid was administered to lymph and portal vein fistula rats. However, when the 14 C-labeled short-chain fatty acids were given, 96–102% of the radioactivity was present as free fatty acids. Studies on the distribution of radioactivity in lipid fractions of portal vein blood showed that 50 and 98–100% of the radioactivity present were in the form of free fatty acids when [ 14 C]oleic acid and 14 C-labeled short-chain fatty acids, respectively, were administered to lymph and portal vein fistula rats." @default.
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- W2016788601 date "1967-04-01" @default.
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- W2016788601 title "Portal absorption of fatty acids in lymph- and portal vein-cannulated rats" @default.
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- W2016788601 doi "https://doi.org/10.1016/0005-2760(67)90105-1" @default.
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