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- W2016801423 abstract "Elevated serum tumor markers after cisplatin-based chemotherapy usually contraindicate surgery because of the presence of active germ-cell elements; however, some patients have undergone PCRPLND with curative intent. We evaluated the role of surgery to resect retroperitoneal-only marker positive tumor. Residual germ-cell cancer was identified in 50% of patients with elevated tumor markers with one third alive at 5 years; 5-year survival with residual teratoma or necrosis was 77.5% and 85.7%, respectively. Predictors of retroperitoneal teratoma or fibrosis included declining tumor makers at surgery, βHCG < 100, and first-line chemotherapy. Predictors of death included rising preoperative βHCG, elevated AFP, redo RPLND, and active germ-cell cancer in the resected specimen. Select patients with elevated tumor markers after chemotherapy are cured with surgery." @default.
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- W2016801423 date "2007-05-01" @default.
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- W2016801423 title "Post Chemotherapy RPLND in Patients with Elevated Markers: Current Concepts and Clinical Outcome" @default.
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- W2016801423 doi "https://doi.org/10.1016/j.ucl.2007.02.006" @default.
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