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- W2016803181 abstract "HEPATIC toxicity due to antimetabolite therapy is a well known complication in the treatment of leukemia. To our knowledge, hepatic damage resulting in portal hypertension and hypersplenism has not been reported as a complication of such therapy.The case reported below describes portal hypertension with bleeding esophageal varices and hypersplenism in a child with a long-term survival with acute lymphocytic leukemia. The patient has been on continuous chemotherapy for the past 10 years, and at the time of this report the disease is still in remission.Case ReportA 6 1/2-year-old girl, previously well, was admitted to the hospital because . . ." @default.
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- W2016803181 date "1968-08-08" @default.
- W2016803181 modified "2023-09-23" @default.
- W2016803181 title "Portal Hypertension in a Case of Acute Leukemia Treated with Antimetabolites for Ten Years" @default.
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- W2016803181 doi "https://doi.org/10.1056/nejm196808082790608" @default.
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