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- W2016806552 abstract "The reaction of amide and thioamide dianions with epibromohydrin resulted in regioselective formation of 5-(hydroxy-methyl)pyrrolidin-2-ones (pyroglutaminols) and -thiones. The cyclization of the dianion of N-(2-tert-butylphenyl)acetamide with epibromohydrin afforded racemic axially chiral 1-(2-tert-butylphenyl)-5-(hydroxymethyl)pyrrolidin-2-one with high diastereoselectivity." @default.
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- W2016806552 date "2006-10-17" @default.
- W2016806552 modified "2023-09-25" @default.
- W2016806552 title "Synthesis of 5-(Hydroxymethyl)pyrrolidin-2-ones by Cyclization of Amide Dianions with Epibromohydrin." @default.
- W2016806552 doi "https://doi.org/10.1002/chin.200642104" @default.
- W2016806552 hasPublicationYear "2006" @default.
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