Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016819133> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2016819133 endingPage "351" @default.
- W2016819133 startingPage "340" @default.
- W2016819133 abstract "Hybrids derived from the fusion of cell lines representing different maturation stages were studied for their membrane and cellular immunoglobulin expression. The hybrids can be subdivided into 3 groups, with one common parental line in each group. In the first group, Raji cells represent the common parent: it contains small amounts of membrane and cytoplasmic mu (t) and kappa (x) chains. In the second group, PUT is the common parent, an ouabain and TG-resistant subline of the BL-derived P3HR-1 line. PUT contains a truncated intracellular t chain. The third group consists of hybrids between K562, an EBV-negative human erythroleukemia line and 2 different BL lines. Membrane-immunoglobulin expression was intermediate between the parental lines in the first two groups derived from the fusion of 2 BL lines. In the third group, hybridization with the K562 cell suppressed the membrane-Ig expression of the B-cell partner. Total cellular immunoglobulin determinations showed that some cells synthesized light chains in excess of heavy chains, others contained an excess of heavy chains, while still others had equal amounts of heavy and light chains. The hybrids showed a variety of patterns, including amplification of the parental phenotypes, appearance of new phenotypic combinations, and eclipse of one or both parental phenotypes. A comparison of the total and the membrane-associated immunoglobulin patterns suggests independent handling of intracellular and membrane immunoglobulin synthesis." @default.
- W2016819133 created "2016-06-24" @default.
- W2016819133 creator A5042561594 @default.
- W2016819133 creator A5046976693 @default.
- W2016819133 creator A5048793417 @default.
- W2016819133 creator A5058857979 @default.
- W2016819133 creator A5065257937 @default.
- W2016819133 creator A5086249933 @default.
- W2016819133 date "1981-12-01" @default.
- W2016819133 modified "2023-10-01" @default.
- W2016819133 title "Membrane-bound and cellular immunoglobulins in human B-lymphoma lines and derived hybrids" @default.
- W2016819133 cites W1893651774 @default.
- W2016819133 cites W1911304984 @default.
- W2016819133 cites W1963704405 @default.
- W2016819133 cites W2018698689 @default.
- W2016819133 cites W2037082529 @default.
- W2016819133 cites W2038901856 @default.
- W2016819133 cites W2058809000 @default.
- W2016819133 cites W2089218050 @default.
- W2016819133 cites W2114090617 @default.
- W2016819133 cites W2168582694 @default.
- W2016819133 cites W2320954544 @default.
- W2016819133 cites W4230542335 @default.
- W2016819133 doi "https://doi.org/10.1016/s0171-2985(81)80060-5" @default.
- W2016819133 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6799389" @default.
- W2016819133 hasPublicationYear "1981" @default.
- W2016819133 type Work @default.
- W2016819133 sameAs 2016819133 @default.
- W2016819133 citedByCount "4" @default.
- W2016819133 crossrefType "journal-article" @default.
- W2016819133 hasAuthorship W2016819133A5042561594 @default.
- W2016819133 hasAuthorship W2016819133A5046976693 @default.
- W2016819133 hasAuthorship W2016819133A5048793417 @default.
- W2016819133 hasAuthorship W2016819133A5058857979 @default.
- W2016819133 hasAuthorship W2016819133A5065257937 @default.
- W2016819133 hasAuthorship W2016819133A5086249933 @default.
- W2016819133 hasConcept C153911025 @default.
- W2016819133 hasConcept C159654299 @default.
- W2016819133 hasConcept C16232356 @default.
- W2016819133 hasConcept C171122931 @default.
- W2016819133 hasConcept C36394416 @default.
- W2016819133 hasConcept C48189365 @default.
- W2016819133 hasConcept C54355233 @default.
- W2016819133 hasConcept C59822182 @default.
- W2016819133 hasConcept C79879829 @default.
- W2016819133 hasConcept C81885089 @default.
- W2016819133 hasConcept C86803240 @default.
- W2016819133 hasConcept C96007430 @default.
- W2016819133 hasConceptScore W2016819133C153911025 @default.
- W2016819133 hasConceptScore W2016819133C159654299 @default.
- W2016819133 hasConceptScore W2016819133C16232356 @default.
- W2016819133 hasConceptScore W2016819133C171122931 @default.
- W2016819133 hasConceptScore W2016819133C36394416 @default.
- W2016819133 hasConceptScore W2016819133C48189365 @default.
- W2016819133 hasConceptScore W2016819133C54355233 @default.
- W2016819133 hasConceptScore W2016819133C59822182 @default.
- W2016819133 hasConceptScore W2016819133C79879829 @default.
- W2016819133 hasConceptScore W2016819133C81885089 @default.
- W2016819133 hasConceptScore W2016819133C86803240 @default.
- W2016819133 hasConceptScore W2016819133C96007430 @default.
- W2016819133 hasIssue "3-4" @default.
- W2016819133 hasLocation W20168191331 @default.
- W2016819133 hasLocation W20168191332 @default.
- W2016819133 hasOpenAccess W2016819133 @default.
- W2016819133 hasPrimaryLocation W20168191331 @default.
- W2016819133 hasRelatedWork W1567456473 @default.
- W2016819133 hasRelatedWork W1658725198 @default.
- W2016819133 hasRelatedWork W1717010705 @default.
- W2016819133 hasRelatedWork W2016819133 @default.
- W2016819133 hasRelatedWork W2038664415 @default.
- W2016819133 hasRelatedWork W2132954980 @default.
- W2016819133 hasRelatedWork W2133159579 @default.
- W2016819133 hasRelatedWork W2332431710 @default.
- W2016819133 hasRelatedWork W2398214774 @default.
- W2016819133 hasRelatedWork W2474091620 @default.
- W2016819133 hasVolume "160" @default.
- W2016819133 isParatext "false" @default.
- W2016819133 isRetracted "false" @default.
- W2016819133 magId "2016819133" @default.
- W2016819133 workType "article" @default.