FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016824226> ?p ?o ?g. }

• W2016824226 endingPage "5832" @default.
• W2016824226 startingPage "5812" @default.
• W2016824226 abstract "The RNA polymerase holoenzyme is a proven target for antibacterial agents. A high-throughput screening program based on this enzyme from Staphylococcus aureus had previously identified a 2-ureidothiophene-3-carboxylate as a low micromolar inhibitor. An investigation of the relationships between the structures of this class of compounds and their inhibitory- and antibacterial activities is described here, leading to a set of potent RNA polymerase inhibitors with antibacterial activity. Characterization of this bioactivity, including studies of the mechanism of action, is provided, highlighting the power of the reverse chemical genetics approach in providing tools to inhibit the bacterial RNA polymerase." @default.
• W2016824226 created "2016-06-24" @default.
• W2016824226 creator A5000317286 @default.
• W2016824226 creator A5003180767 @default.
• W2016824226 creator A5009710802 @default.
• W2016824226 creator A5015641974 @default.
• W2016824226 creator A5018943283 @default.
• W2016824226 creator A5023659945 @default.
• W2016824226 creator A5030449858 @default.
• W2016824226 creator A5033058750 @default.
• W2016824226 creator A5035282947 @default.
• W2016824226 creator A5035547404 @default.
• W2016824226 creator A5045348393 @default.
• W2016824226 creator A5048995010 @default.
• W2016824226 creator A5049771727 @default.
• W2016824226 creator A5063290824 @default.
• W2016824226 creator A5066765662 @default.
• W2016824226 creator A5076939431 @default.
• W2016824226 creator A5079962104 @default.
• W2016824226 creator A5081540385 @default.
• W2016824226 creator A5085950370 @default.
• W2016824226 creator A5088785560 @default.
• W2016824226 creator A5090384213 @default.
• W2016824226 date "2006-09-01" @default.
• W2016824226 modified "2023-09-23" @default.
• W2016824226 title "A new class of small molecule RNA polymerase inhibitors with activity against Rifampicin-resistant Staphylococcus aureus1" @default.
• W2016824226 cites W1582517124 @default.
• W2016824226 cites W1965768900 @default.
• W2016824226 cites W1968386878 @default.
• W2016824226 cites W1980640885 @default.
• W2016824226 cites W1985701256 @default.
• W2016824226 cites W2002592515 @default.
• W2016824226 cites W2004490137 @default.
• W2016824226 cites W2005156172 @default.
• W2016824226 cites W2008231765 @default.
• W2016824226 cites W2011968916 @default.
• W2016824226 cites W2026457513 @default.
• W2016824226 cites W2029869659 @default.
• W2016824226 cites W2034232865 @default.
• W2016824226 cites W2049151141 @default.
• W2016824226 cites W2055506322 @default.
• W2016824226 cites W2073648757 @default.
• W2016824226 cites W2076922800 @default.
• W2016824226 cites W2085313140 @default.
• W2016824226 cites W2090286010 @default.
• W2016824226 cites W2097743603 @default.
• W2016824226 cites W2137749088 @default.
• W2016824226 cites W2314649741 @default.
• W2016824226 cites W2952117608 @default.
• W2016824226 doi "https://doi.org/10.1016/j.bmc.2006.05.035" @default.
• W2016824226 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16759869" @default.
• W2016824226 hasPublicationYear "2006" @default.
• W2016824226 type Work @default.
• W2016824226 sameAs 2016824226 @default.
• W2016824226 citedByCount "37" @default.
• W2016824226 countsByYear W20168242262012 @default.
• W2016824226 countsByYear W20168242262013 @default.
• W2016824226 countsByYear W20168242262014 @default.
• W2016824226 countsByYear W20168242262016 @default.
• W2016824226 countsByYear W20168242262018 @default.
• W2016824226 countsByYear W20168242262020 @default.
• W2016824226 countsByYear W20168242262022 @default.
• W2016824226 countsByYear W20168242262023 @default.
• W2016824226 crossrefType "journal-article" @default.
• W2016824226 hasAuthorship W2016824226A5000317286 @default.
• W2016824226 hasAuthorship W2016824226A5003180767 @default.
• W2016824226 hasAuthorship W2016824226A5009710802 @default.
• W2016824226 hasAuthorship W2016824226A5015641974 @default.
• W2016824226 hasAuthorship W2016824226A5018943283 @default.
• W2016824226 hasAuthorship W2016824226A5023659945 @default.
• W2016824226 hasAuthorship W2016824226A5030449858 @default.
• W2016824226 hasAuthorship W2016824226A5033058750 @default.
• W2016824226 hasAuthorship W2016824226A5035282947 @default.
• W2016824226 hasAuthorship W2016824226A5035547404 @default.
• W2016824226 hasAuthorship W2016824226A5045348393 @default.
• W2016824226 hasAuthorship W2016824226A5048995010 @default.
• W2016824226 hasAuthorship W2016824226A5049771727 @default.
• W2016824226 hasAuthorship W2016824226A5063290824 @default.
• W2016824226 hasAuthorship W2016824226A5066765662 @default.
• W2016824226 hasAuthorship W2016824226A5076939431 @default.
• W2016824226 hasAuthorship W2016824226A5079962104 @default.
• W2016824226 hasAuthorship W2016824226A5081540385 @default.
• W2016824226 hasAuthorship W2016824226A5085950370 @default.
• W2016824226 hasAuthorship W2016824226A5088785560 @default.
• W2016824226 hasAuthorship W2016824226A5090384213 @default.
• W2016824226 hasConcept C104317684 @default.
• W2016824226 hasConcept C181199279 @default.
• W2016824226 hasConcept C185592680 @default.
• W2016824226 hasConcept C202751555 @default.
• W2016824226 hasConcept C2776120743 @default.
• W2016824226 hasConcept C2776449523 @default.
• W2016824226 hasConcept C2778607973 @default.
• W2016824226 hasConcept C2779489039 @default.
• W2016824226 hasConcept C3019249092 @default.
• W2016824226 hasConcept C501593827 @default.
• W2016824226 hasConcept C523546767 @default.
• W2016824226 hasConcept C54355233 @default.
• W2016824226 hasConcept C55493867 @default.

• next