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• W2016847013 abstract "RationaleThe aim of this study was to investigate the incidence and trend of comorbid conditons of obesity, gastroesophageal reflux and sleep apnea developed among asthma patients during 5 years period.MethodsThis study was based on continuous data from the Taiwanese National Health Insurance Research Database which contained 98% of registry files of all 22.60 million populations. Asthma was selected with code 493.xx of the International Classification of Disease, 9th Revision, Clinical Modification. Asthma case was defined that the diagnosis occurred more than three times within 6 months. A total 139,629 (74,603 in male, 65,026 in female) patients newly diagnosed with asthma in 2003 were enrolled in this cohort and follow-up. Each disease was defined with corresponding ICD-9 code.ResultsThere were 0.01% of asthma patients suffering from sleep apnea in year 2003 and increased to 0.07% in year 2008. The associated sleep apnea increased from 0.02% to 0.11% in male asthma patients, which is more common than females (from 0.01 to 0.04, p<0.001). It was 0.3% of asthma patients with obesity which was significant higher than non-asthma populations. Female asthma patients had more common with this problem than males (0.42% vs 0.2%, p<0.001). In 2003, it was 0.04% of asthma patients had gastroesophageal reflux, and 0.01% in non-asthma populations (p<0.001). It increased to 0.56% and 0.30% respectively in 2008 (p<0.001). Female patients increased more prominently with this problem than males.ConclusionsMale asthma patients had increasing trend to develop sleep apnea, and female patients had increasing trend in gastroesophageal reflux. RationaleThe aim of this study was to investigate the incidence and trend of comorbid conditons of obesity, gastroesophageal reflux and sleep apnea developed among asthma patients during 5 years period. The aim of this study was to investigate the incidence and trend of comorbid conditons of obesity, gastroesophageal reflux and sleep apnea developed among asthma patients during 5 years period. MethodsThis study was based on continuous data from the Taiwanese National Health Insurance Research Database which contained 98% of registry files of all 22.60 million populations. Asthma was selected with code 493.xx of the International Classification of Disease, 9th Revision, Clinical Modification. Asthma case was defined that the diagnosis occurred more than three times within 6 months. A total 139,629 (74,603 in male, 65,026 in female) patients newly diagnosed with asthma in 2003 were enrolled in this cohort and follow-up. Each disease was defined with corresponding ICD-9 code. This study was based on continuous data from the Taiwanese National Health Insurance Research Database which contained 98% of registry files of all 22.60 million populations. Asthma was selected with code 493.xx of the International Classification of Disease, 9th Revision, Clinical Modification. Asthma case was defined that the diagnosis occurred more than three times within 6 months. A total 139,629 (74,603 in male, 65,026 in female) patients newly diagnosed with asthma in 2003 were enrolled in this cohort and follow-up. Each disease was defined with corresponding ICD-9 code. ResultsThere were 0.01% of asthma patients suffering from sleep apnea in year 2003 and increased to 0.07% in year 2008. The associated sleep apnea increased from 0.02% to 0.11% in male asthma patients, which is more common than females (from 0.01 to 0.04, p<0.001). It was 0.3% of asthma patients with obesity which was significant higher than non-asthma populations. Female asthma patients had more common with this problem than males (0.42% vs 0.2%, p<0.001). In 2003, it was 0.04% of asthma patients had gastroesophageal reflux, and 0.01% in non-asthma populations (p<0.001). It increased to 0.56% and 0.30% respectively in 2008 (p<0.001). Female patients increased more prominently with this problem than males. There were 0.01% of asthma patients suffering from sleep apnea in year 2003 and increased to 0.07% in year 2008. The associated sleep apnea increased from 0.02% to 0.11% in male asthma patients, which is more common than females (from 0.01 to 0.04, p<0.001). It was 0.3% of asthma patients with obesity which was significant higher than non-asthma populations. Female asthma patients had more common with this problem than males (0.42% vs 0.2%, p<0.001). In 2003, it was 0.04% of asthma patients had gastroesophageal reflux, and 0.01% in non-asthma populations (p<0.001). It increased to 0.56% and 0.30% respectively in 2008 (p<0.001). Female patients increased more prominently with this problem than males. ConclusionsMale asthma patients had increasing trend to develop sleep apnea, and female patients had increasing trend in gastroesophageal reflux. Male asthma patients had increasing trend to develop sleep apnea, and female patients had increasing trend in gastroesophageal reflux." @default.
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• W2016847013 date "2012-02-01" @default.
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• W2016847013 title "Trend of Asthma Comorbidities of Sleep Apnea, Obesity, and Gastroesophageal Reflux - A 5-year Population Survey" @default.
• W2016847013 doi "https://doi.org/10.1016/j.jaci.2011.12.312" @default.
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