FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016857154> ?p ?o ?g. }

• W2016857154 endingPage "145" @default.
• W2016857154 startingPage "139" @default.
• W2016857154 abstract "Acute anemic stress induces a physiological response that includes the rapid development of new erythrocytes. This process is referred to as stress erythropoiesis, which is distinct from steady state erythropoiesis. Much of what we know about stress erythropoiesis comes from the analysis of murine models. In this review, we will discuss our current understanding of the mechanisms that regulate stress erythropoiesis in mice and discuss outstanding questions in the field.Stress erythropoiesis occurs in the murine spleen, fetal liver and adult liver. The signals that regulate this process are Hedgehog, bone morphogenetic protein 4 (BMP4), stem cell factor and hypoxia. Recent findings show that stress erythropoiesis utilizes a population of erythroid-restricted self-renewing stress progenitors. Although the BMP4-dependent stress erythropoiesis pathway was first characterized during the recovery from acute anemia, analysis of a mouse model of chronic anemia demonstrated that activation of the BMP4-dependent stress erythropoiesis pathway provides compensatory erythropoiesis in response to chronic anemia as well.The BMP4-dependent stress erythropoiesis pathway plays a key role in the recovery from acute anemia and new data show that this pathway compensates for ineffective steady state erythropoiesis in a murine model of chronic anemia. The identification of a self-renewing population of stress erythroid progenitors in mice suggests that therapeutic manipulation of this pathway may be useful for the treatment of human anemia. However, the development of new therapies will await the characterization of an analogous pathway in humans." @default.
• W2016857154 created "2016-06-24" @default.
• W2016857154 creator A5016440386 @default.
• W2016857154 creator A5027634820 @default.
• W2016857154 creator A5061521684 @default.
• W2016857154 date "2011-05-01" @default.
• W2016857154 modified "2023-09-30" @default.
• W2016857154 title "Stress erythropoiesis: new signals and new stress progenitor cells" @default.
• W2016857154 cites W1535560730 @default.
• W2016857154 cites W1607672962 @default.
• W2016857154 cites W186338728 @default.
• W2016857154 cites W1923812448 @default.
• W2016857154 cites W1944811154 @default.
• W2016857154 cites W1966144382 @default.
• W2016857154 cites W1972735584 @default.
• W2016857154 cites W1972943035 @default.
• W2016857154 cites W1975489205 @default.
• W2016857154 cites W1976321898 @default.
• W2016857154 cites W1986828704 @default.
• W2016857154 cites W2009703598 @default.
• W2016857154 cites W2010599622 @default.
• W2016857154 cites W2011126711 @default.
• W2016857154 cites W2024174149 @default.
• W2016857154 cites W2025837031 @default.
• W2016857154 cites W2027924602 @default.
• W2016857154 cites W2035494124 @default.
• W2016857154 cites W2035875161 @default.
• W2016857154 cites W2037695813 @default.
• W2016857154 cites W2041897320 @default.
• W2016857154 cites W2044898737 @default.
• W2016857154 cites W2045738244 @default.
• W2016857154 cites W2048850912 @default.
• W2016857154 cites W2051066066 @default.
• W2016857154 cites W2051282428 @default.
• W2016857154 cites W2053905675 @default.
• W2016857154 cites W2054574471 @default.
• W2016857154 cites W2055610467 @default.
• W2016857154 cites W2057582400 @default.
• W2016857154 cites W2058521603 @default.
• W2016857154 cites W2058619114 @default.
• W2016857154 cites W2063436204 @default.
• W2016857154 cites W2064552742 @default.
• W2016857154 cites W2065083959 @default.
• W2016857154 cites W2067348966 @default.
• W2016857154 cites W2073246218 @default.
• W2016857154 cites W2073701271 @default.
• W2016857154 cites W2073895217 @default.
• W2016857154 cites W2076132676 @default.
• W2016857154 cites W2083632015 @default.
• W2016857154 cites W2085030824 @default.
• W2016857154 cites W2088024298 @default.
• W2016857154 cites W2091571816 @default.
• W2016857154 cites W2095605427 @default.
• W2016857154 cites W2099509414 @default.
• W2016857154 cites W2100564935 @default.
• W2016857154 cites W2101821342 @default.
• W2016857154 cites W2112811492 @default.
• W2016857154 cites W2118308240 @default.
• W2016857154 cites W2123200029 @default.
• W2016857154 cites W2138159844 @default.
• W2016857154 cites W2139685741 @default.
• W2016857154 cites W2140922568 @default.
• W2016857154 cites W2149751735 @default.
• W2016857154 cites W2164322506 @default.
• W2016857154 cites W2168306631 @default.
• W2016857154 cites W2169154746 @default.
• W2016857154 cites W2171702968 @default.
• W2016857154 cites W2313150609 @default.
• W2016857154 cites W2412563778 @default.
• W2016857154 cites W30417596 @default.
• W2016857154 doi "https://doi.org/10.1097/moh.0b013e32834521c8" @default.
• W2016857154 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3099455" @default.
• W2016857154 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21372709" @default.
• W2016857154 hasPublicationYear "2011" @default.
• W2016857154 type Work @default.
• W2016857154 sameAs 2016857154 @default.
• W2016857154 citedByCount "197" @default.
• W2016857154 countsByYear W20168571542012 @default.
• W2016857154 countsByYear W20168571542013 @default.
• W2016857154 countsByYear W20168571542014 @default.
• W2016857154 countsByYear W20168571542015 @default.
• W2016857154 countsByYear W20168571542016 @default.
• W2016857154 countsByYear W20168571542017 @default.
• W2016857154 countsByYear W20168571542018 @default.
• W2016857154 countsByYear W20168571542019 @default.
• W2016857154 countsByYear W20168571542020 @default.
• W2016857154 countsByYear W20168571542021 @default.
• W2016857154 countsByYear W20168571542022 @default.
• W2016857154 countsByYear W20168571542023 @default.
• W2016857154 crossrefType "journal-article" @default.
• W2016857154 hasAuthorship W2016857154A5016440386 @default.
• W2016857154 hasAuthorship W2016857154A5027634820 @default.
• W2016857154 hasAuthorship W2016857154A5061521684 @default.
• W2016857154 hasBestOaLocation W20168571542 @default.
• W2016857154 hasConcept C126322002 @default.
• W2016857154 hasConcept C134018914 @default.
• W2016857154 hasConcept C201750760 @default.
• W2016857154 hasConcept C203014093 @default.

• next