FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016893089> ?p ?o ?g. }

• W2016893089 endingPage "169" @default.
• W2016893089 startingPage "163" @default.
• W2016893089 abstract "Psammaplin A (PsA) is a phenolic natural product isolated from a marine sponge, which showed a potent cytotoxicity against several cancer cell lines. In present study, PsA was found to inhibit mammalian aminopeptidase N (APN) that plays a key role in tumor cell invasion and angiogenesis. PsA inhibited the APN activity with an IC50 of 18 microM in a non-competitive manner. Moreover, PsA potently inhibited the proliferation of several cancer and endothelial cells. Interestingly, the anti-proliferative effect of PsA was dependent on the cellular amount of APN expression. Finally, PsA suppressed the invasion and tube formation of endothelial cells stimulated by basic fibroblast growth factor. These data demonstrate that PsA is a new inhibitor of APN and can be developed as a novel anti-angiogenic agent." @default.
• W2016893089 created "2016-06-24" @default.
• W2016893089 creator A5010093750 @default.
• W2016893089 creator A5020875849 @default.
• W2016893089 creator A5045827347 @default.
• W2016893089 creator A5067684286 @default.
• W2016893089 date "2004-01-01" @default.
• W2016893089 modified "2023-09-26" @default.
• W2016893089 title "Psammaplin A, a marine natural product, inhibits aminopeptidase N and suppresses angiogenesis in vitro" @default.
• W2016893089 cites W1587947784 @default.
• W2016893089 cites W173844952 @default.
• W2016893089 cites W1968858321 @default.
• W2016893089 cites W1980036500 @default.
• W2016893089 cites W1981591956 @default.
• W2016893089 cites W1981612052 @default.
• W2016893089 cites W1985804036 @default.
• W2016893089 cites W1985971242 @default.
• W2016893089 cites W2003598961 @default.
• W2016893089 cites W2013044761 @default.
• W2016893089 cites W2047643480 @default.
• W2016893089 cites W2048802496 @default.
• W2016893089 cites W2091246008 @default.
• W2016893089 cites W2107257265 @default.
• W2016893089 cites W2146875307 @default.
• W2016893089 cites W2951110259 @default.
• W2016893089 cites W4211002736 @default.
• W2016893089 doi "https://doi.org/10.1016/j.canlet.2003.08.036" @default.
• W2016893089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14732224" @default.
• W2016893089 hasPublicationYear "2004" @default.
• W2016893089 type Work @default.
• W2016893089 sameAs 2016893089 @default.
• W2016893089 citedByCount "67" @default.
• W2016893089 countsByYear W20168930892012 @default.
• W2016893089 countsByYear W20168930892013 @default.
• W2016893089 countsByYear W20168930892014 @default.
• W2016893089 countsByYear W20168930892015 @default.
• W2016893089 countsByYear W20168930892016 @default.
• W2016893089 countsByYear W20168930892018 @default.
• W2016893089 countsByYear W20168930892019 @default.
• W2016893089 countsByYear W20168930892020 @default.
• W2016893089 countsByYear W20168930892021 @default.
• W2016893089 countsByYear W20168930892022 @default.
• W2016893089 countsByYear W20168930892023 @default.
• W2016893089 crossrefType "journal-article" @default.
• W2016893089 hasAuthorship W2016893089A5010093750 @default.
• W2016893089 hasAuthorship W2016893089A5020875849 @default.
• W2016893089 hasAuthorship W2016893089A5045827347 @default.
• W2016893089 hasAuthorship W2016893089A5067684286 @default.
• W2016893089 hasConcept C109316439 @default.
• W2016893089 hasConcept C185592680 @default.
• W2016893089 hasConcept C202751555 @default.
• W2016893089 hasConcept C2776056115 @default.
• W2016893089 hasConcept C2776580952 @default.
• W2016893089 hasConcept C2779396153 @default.
• W2016893089 hasConcept C2780394083 @default.
• W2016893089 hasConcept C2780985610 @default.
• W2016893089 hasConcept C502942594 @default.
• W2016893089 hasConcept C515207424 @default.
• W2016893089 hasConcept C54355233 @default.
• W2016893089 hasConcept C55493867 @default.
• W2016893089 hasConcept C62112901 @default.
• W2016893089 hasConcept C81885089 @default.
• W2016893089 hasConcept C86803240 @default.
• W2016893089 hasConcept C95444343 @default.
• W2016893089 hasConceptScore W2016893089C109316439 @default.
• W2016893089 hasConceptScore W2016893089C185592680 @default.
• W2016893089 hasConceptScore W2016893089C202751555 @default.
• W2016893089 hasConceptScore W2016893089C2776056115 @default.
• W2016893089 hasConceptScore W2016893089C2776580952 @default.
• W2016893089 hasConceptScore W2016893089C2779396153 @default.
• W2016893089 hasConceptScore W2016893089C2780394083 @default.
• W2016893089 hasConceptScore W2016893089C2780985610 @default.
• W2016893089 hasConceptScore W2016893089C502942594 @default.
• W2016893089 hasConceptScore W2016893089C515207424 @default.
• W2016893089 hasConceptScore W2016893089C54355233 @default.
• W2016893089 hasConceptScore W2016893089C55493867 @default.
• W2016893089 hasConceptScore W2016893089C62112901 @default.
• W2016893089 hasConceptScore W2016893089C81885089 @default.
• W2016893089 hasConceptScore W2016893089C86803240 @default.
• W2016893089 hasConceptScore W2016893089C95444343 @default.
• W2016893089 hasIssue "2" @default.
• W2016893089 hasLocation W20168930891 @default.
• W2016893089 hasLocation W20168930892 @default.
• W2016893089 hasOpenAccess W2016893089 @default.
• W2016893089 hasPrimaryLocation W20168930891 @default.
• W2016893089 hasRelatedWork W1842687350 @default.
• W2016893089 hasRelatedWork W1983822371 @default.
• W2016893089 hasRelatedWork W1999272804 @default.
• W2016893089 hasRelatedWork W2016893089 @default.
• W2016893089 hasRelatedWork W2031724886 @default.
• W2016893089 hasRelatedWork W2330870928 @default.
• W2016893089 hasRelatedWork W2464301138 @default.
• W2016893089 hasRelatedWork W3046142566 @default.
• W2016893089 hasRelatedWork W3178515596 @default.
• W2016893089 hasRelatedWork W4213260161 @default.
• W2016893089 hasVolume "203" @default.
• W2016893089 isParatext "false" @default.
• W2016893089 isRetracted "false" @default.

• next