Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016928161> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2016928161 endingPage "250" @default.
- W2016928161 startingPage "243" @default.
- W2016928161 abstract "Chemical and biochemical studies were performed on two unrelated fetuses affected with Niemann-Pick disease type A, following abortion at about the 19th week of gestation. Abortion was performed as a consequence of previous findings, in amniotic fluid cell cultures, that sphingomyelinase activity was completely absent. Phospholipid analyses of various organs of the fetuses revealed an excess of sphingomyelin in all viscera as compared to control nonaffected fetuses. Spleen and liver were the organs mostly affected. Interestingly enough considerable accumulation of sphingomyelin was found in the placenta. The brain was the only organ in which sphingomyelin storage could not be proved. In addition to sphingomyelin a slight accumulation of cholesterol was noticed. Deficiency of sphingomyelinase activity measured at pH 5.0 was the general characteristics of the affected tissues. It could be concluded that the accumulation of sphingomyelin in various organs throughout the body of fetuses affected with Niemann-Pick disease, was suggestive of the essential role of the enzyme sphingomyelinase and its biochemical maturation, even during the early stages of gestation." @default.
- W2016928161 created "2016-06-24" @default.
- W2016928161 creator A5031467053 @default.
- W2016928161 creator A5035382874 @default.
- W2016928161 creator A5062327983 @default.
- W2016928161 creator A5069351105 @default.
- W2016928161 date "1979-02-01" @default.
- W2016928161 modified "2023-09-26" @default.
- W2016928161 title "Chemical and biochemical studies in human fetuses affected with niemann-pick disease type a" @default.
- W2016928161 cites W1522146362 @default.
- W2016928161 cites W1671911349 @default.
- W2016928161 cites W1775749144 @default.
- W2016928161 cites W1931677656 @default.
- W2016928161 cites W1975116170 @default.
- W2016928161 cites W1980021409 @default.
- W2016928161 cites W1989581601 @default.
- W2016928161 cites W1990246608 @default.
- W2016928161 cites W1993038465 @default.
- W2016928161 cites W2000533954 @default.
- W2016928161 cites W2009293194 @default.
- W2016928161 cites W2010095354 @default.
- W2016928161 cites W2013955153 @default.
- W2016928161 cites W2015307443 @default.
- W2016928161 cites W2048192611 @default.
- W2016928161 cites W2082773053 @default.
- W2016928161 cites W2111892802 @default.
- W2016928161 cites W2135816568 @default.
- W2016928161 doi "https://doi.org/10.1016/0009-8981(79)90480-7" @default.
- W2016928161 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/761400" @default.
- W2016928161 hasPublicationYear "1979" @default.
- W2016928161 type Work @default.
- W2016928161 sameAs 2016928161 @default.
- W2016928161 citedByCount "8" @default.
- W2016928161 crossrefType "journal-article" @default.
- W2016928161 hasAuthorship W2016928161A5031467053 @default.
- W2016928161 hasAuthorship W2016928161A5035382874 @default.
- W2016928161 hasAuthorship W2016928161A5062327983 @default.
- W2016928161 hasAuthorship W2016928161A5069351105 @default.
- W2016928161 hasConcept C126322002 @default.
- W2016928161 hasConcept C134018914 @default.
- W2016928161 hasConcept C16685009 @default.
- W2016928161 hasConcept C172680121 @default.
- W2016928161 hasConcept C2776953305 @default.
- W2016928161 hasConcept C2778163477 @default.
- W2016928161 hasConcept C2778194526 @default.
- W2016928161 hasConcept C2778918659 @default.
- W2016928161 hasConcept C2779234561 @default.
- W2016928161 hasConcept C2779489717 @default.
- W2016928161 hasConcept C2781070647 @default.
- W2016928161 hasConcept C2781457462 @default.
- W2016928161 hasConcept C41625074 @default.
- W2016928161 hasConcept C46973012 @default.
- W2016928161 hasConcept C54355233 @default.
- W2016928161 hasConcept C55493867 @default.
- W2016928161 hasConcept C61322309 @default.
- W2016928161 hasConcept C71924100 @default.
- W2016928161 hasConcept C86803240 @default.
- W2016928161 hasConceptScore W2016928161C126322002 @default.
- W2016928161 hasConceptScore W2016928161C134018914 @default.
- W2016928161 hasConceptScore W2016928161C16685009 @default.
- W2016928161 hasConceptScore W2016928161C172680121 @default.
- W2016928161 hasConceptScore W2016928161C2776953305 @default.
- W2016928161 hasConceptScore W2016928161C2778163477 @default.
- W2016928161 hasConceptScore W2016928161C2778194526 @default.
- W2016928161 hasConceptScore W2016928161C2778918659 @default.
- W2016928161 hasConceptScore W2016928161C2779234561 @default.
- W2016928161 hasConceptScore W2016928161C2779489717 @default.
- W2016928161 hasConceptScore W2016928161C2781070647 @default.
- W2016928161 hasConceptScore W2016928161C2781457462 @default.
- W2016928161 hasConceptScore W2016928161C41625074 @default.
- W2016928161 hasConceptScore W2016928161C46973012 @default.
- W2016928161 hasConceptScore W2016928161C54355233 @default.
- W2016928161 hasConceptScore W2016928161C55493867 @default.
- W2016928161 hasConceptScore W2016928161C61322309 @default.
- W2016928161 hasConceptScore W2016928161C71924100 @default.
- W2016928161 hasConceptScore W2016928161C86803240 @default.
- W2016928161 hasIssue "3" @default.
- W2016928161 hasLocation W20169281611 @default.
- W2016928161 hasLocation W20169281612 @default.
- W2016928161 hasOpenAccess W2016928161 @default.
- W2016928161 hasPrimaryLocation W20169281611 @default.
- W2016928161 hasRelatedWork W1993795923 @default.
- W2016928161 hasRelatedWork W2013144555 @default.
- W2016928161 hasRelatedWork W2016928161 @default.
- W2016928161 hasRelatedWork W2039466440 @default.
- W2016928161 hasRelatedWork W2056344898 @default.
- W2016928161 hasRelatedWork W205687916 @default.
- W2016928161 hasRelatedWork W2121985916 @default.
- W2016928161 hasRelatedWork W2131811784 @default.
- W2016928161 hasRelatedWork W2146585071 @default.
- W2016928161 hasRelatedWork W4321168886 @default.
- W2016928161 hasVolume "91" @default.
- W2016928161 isParatext "false" @default.
- W2016928161 isRetracted "false" @default.
- W2016928161 magId "2016928161" @default.
- W2016928161 workType "article" @default.