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- W2016943933 abstract "The neuromuscular blocking effects of a single dose of rapacuronium 1.5 mg.kg−1 with or without reversal with neostigmine have been examined in the present study and compared with a dose of succinylcholine 1.0 mg.kg−1. Neuromuscular block was measured mechanomyographically using train-of-four stimulation. Complete block occurred within 1 min with both agents. Twenty-five per cent recovery of the first response of the train-of-four occurred in a median [range] time of 7.6 [5.7–11.3] min in the succinylcholine group and in 14.2 [8.8–23.6] and 15.1 [9.6–23.4] min in the rapacuronium groups with and without neostigmine reversal, respectively. Spontaneous recovery to a train-of-four ratio of 0.8 took 33.4 [20.0–79.0] min with rapacuronium but this was reduced to about 21.2 [13.9–33.7] min when neostigmine was administered at 25% recovery of first twitch of the train-of-four." @default.
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- W2016943933 date "2000-09-26" @default.
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- W2016943933 title "Comparison of recovery following rapacuronium, with and without neostigmine, and succinylcholine" @default.
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- W2016943933 doi "https://doi.org/10.1046/j.1365-2044.2000.01541.x" @default.
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