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- W2016945285 abstract "Ran protein is a central molecular in several key nuclear functions, including nucleocytoplasmic transport, cell-cycle progression and nuclear envelope assembly. In this study, we have isolated and characterized a Ran homologue from a gastropod abalone which we named ab-Ran. The full-length cDNA consists of 1239 bp with an ORF encoding a 220 amino acid protein. The deduced amino acid sequence of ab-Ran shows highly similar to that of other Ran members (84-88%). Moreover, the ab-Ran contains five conserved regions and four carboxy-terminal residues CAAX-box. RT-PCR analysis showed that the ab-Ran was ubiquitously expressed in abalone tissues. The intracellular localization examined by immunofluorescence and immunohistochemistry staining displayed that ab-Ran was largely concentrated in the nuclei and partially in the cytoplasm. To the best of our knowledge, this is the first identification and characterization of a Ran homologue in mollusk." @default.
- W2016945285 created "2016-06-24" @default.
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- W2016945285 date "2011-03-01" @default.
- W2016945285 modified "2023-09-27" @default.
- W2016945285 title "Identification and expression localization of a Ran homologue in mollusc abalone, Haliotis diversicolor supertexta" @default.
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- W2016945285 doi "https://doi.org/10.1016/j.fsi.2010.10.024" @default.
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