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- W2016965861 abstract "Abstract Time-resolved fluorescence was studied for two different applications: demarcation of malignant tumours from normal tissue and atherosclerotic plaque of different degrees from normal vessel wall. The time-correlated single-photon counting technique was employed using the second harmonic of a synchronously pumped argon-ion dyel/laser system. The time response of the detection system was approximately 70 ps. The results revealed a fluorescence band peaking at 380 nm with a lifetime of ⋍7 ns specific for atherosclerotic plaque. In this paper we discuss the importance of blood interference in spectroscopic data from vessels and how this can be avoided for a reliable diagnosis. We also present recordings on malignant tumours following systemic injection of Photofrin II. This tumour seeking drug has an effective fluorescence lifetime of ⋍15 ns allowing background-free recordings if delayed detection is used to suppress the more short-lived autofluorescence." @default.
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- W2016965861 title "The use of time-resolved fluorescence for diagnosis of atherosclerotic plaque and malignant tumours" @default.
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- W2016965861 doi "https://doi.org/10.1016/0584-8539(90)80196-6" @default.
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