Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016972335> ?p ?o ?g. }
- W2016972335 endingPage "1295" @default.
- W2016972335 startingPage "1290" @default.
- W2016972335 abstract "An efficient method for the direct labeling of the Arg guanidinium group in native peptides is reported. This straightforward procedure allows modifying the arginine moiety in peptides with various reporter groups, such as fluorophores, biotin, etc., under mild conditions in an operationally simple procedure. The scope of this method tolerates various functionalized amino acids such as His, Ser, Trp, Tyr, Glu, etc., while the only limitations uncovered so far are restricted to cysteine and free amine residues. The utility of this late-stage diversification method was demonstrated in direct labeling of leuprolide, a clinically used drug, for distribution monitoring in Daphnia, and in labeling of microcystin, a cyanobacterial toxin." @default.
- W2016972335 created "2016-06-24" @default.
- W2016972335 creator A5014113644 @default.
- W2016972335 creator A5042260330 @default.
- W2016972335 date "2014-10-31" @default.
- W2016972335 modified "2023-10-15" @default.
- W2016972335 title "Direct Arginine Modification in Native Peptides and Application to Chemical Probe Development" @default.
- W2016972335 cites W105515906 @default.
- W2016972335 cites W1655962167 @default.
- W2016972335 cites W1963683058 @default.
- W2016972335 cites W1973671987 @default.
- W2016972335 cites W1976292782 @default.
- W2016972335 cites W1980866237 @default.
- W2016972335 cites W1987748272 @default.
- W2016972335 cites W1995669318 @default.
- W2016972335 cites W2001678282 @default.
- W2016972335 cites W2001865803 @default.
- W2016972335 cites W2010652575 @default.
- W2016972335 cites W2012803264 @default.
- W2016972335 cites W2021363994 @default.
- W2016972335 cites W2021578686 @default.
- W2016972335 cites W2023979852 @default.
- W2016972335 cites W2025261478 @default.
- W2016972335 cites W2025686590 @default.
- W2016972335 cites W2028161249 @default.
- W2016972335 cites W2030487895 @default.
- W2016972335 cites W2031734182 @default.
- W2016972335 cites W2033172686 @default.
- W2016972335 cites W2034662560 @default.
- W2016972335 cites W2034694458 @default.
- W2016972335 cites W2035646910 @default.
- W2016972335 cites W2041604340 @default.
- W2016972335 cites W2044360583 @default.
- W2016972335 cites W2045301848 @default.
- W2016972335 cites W2047877147 @default.
- W2016972335 cites W2048340373 @default.
- W2016972335 cites W2050000500 @default.
- W2016972335 cites W2058567710 @default.
- W2016972335 cites W2063286278 @default.
- W2016972335 cites W2076143662 @default.
- W2016972335 cites W2077987849 @default.
- W2016972335 cites W2078188118 @default.
- W2016972335 cites W2079962210 @default.
- W2016972335 cites W2082702196 @default.
- W2016972335 cites W2086722398 @default.
- W2016972335 cites W2087094329 @default.
- W2016972335 cites W2095328296 @default.
- W2016972335 cites W2101073852 @default.
- W2016972335 cites W2105468331 @default.
- W2016972335 cites W2130978648 @default.
- W2016972335 cites W2149315069 @default.
- W2016972335 cites W2159626577 @default.
- W2016972335 cites W2167023708 @default.
- W2016972335 cites W2178976395 @default.
- W2016972335 cites W2322836762 @default.
- W2016972335 cites W2949831905 @default.
- W2016972335 doi "https://doi.org/10.1021/ml5003508" @default.
- W2016972335 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4265810" @default.
- W2016972335 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25516786" @default.
- W2016972335 hasPublicationYear "2014" @default.
- W2016972335 type Work @default.
- W2016972335 sameAs 2016972335 @default.
- W2016972335 citedByCount "15" @default.
- W2016972335 countsByYear W20169723352015 @default.
- W2016972335 countsByYear W20169723352016 @default.
- W2016972335 countsByYear W20169723352017 @default.
- W2016972335 countsByYear W20169723352019 @default.
- W2016972335 countsByYear W20169723352021 @default.
- W2016972335 countsByYear W20169723352022 @default.
- W2016972335 countsByYear W20169723352023 @default.
- W2016972335 crossrefType "journal-article" @default.
- W2016972335 hasAuthorship W2016972335A5014113644 @default.
- W2016972335 hasAuthorship W2016972335A5042260330 @default.
- W2016972335 hasBestOaLocation W20169723352 @default.
- W2016972335 hasConcept C181199279 @default.
- W2016972335 hasConcept C185592680 @default.
- W2016972335 hasConcept C21951064 @default.
- W2016972335 hasConcept C2776016237 @default.
- W2016972335 hasConcept C2776568683 @default.
- W2016972335 hasConcept C2777468819 @default.
- W2016972335 hasConcept C2778204606 @default.
- W2016972335 hasConcept C2778460671 @default.
- W2016972335 hasConcept C2779201268 @default.
- W2016972335 hasConcept C515207424 @default.
- W2016972335 hasConcept C55493867 @default.
- W2016972335 hasConcept C70721500 @default.
- W2016972335 hasConcept C71240020 @default.
- W2016972335 hasConcept C86803240 @default.
- W2016972335 hasConceptScore W2016972335C181199279 @default.
- W2016972335 hasConceptScore W2016972335C185592680 @default.
- W2016972335 hasConceptScore W2016972335C21951064 @default.
- W2016972335 hasConceptScore W2016972335C2776016237 @default.
- W2016972335 hasConceptScore W2016972335C2776568683 @default.
- W2016972335 hasConceptScore W2016972335C2777468819 @default.
- W2016972335 hasConceptScore W2016972335C2778204606 @default.
- W2016972335 hasConceptScore W2016972335C2778460671 @default.
- W2016972335 hasConceptScore W2016972335C2779201268 @default.
- W2016972335 hasConceptScore W2016972335C515207424 @default.