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• W2016979253 abstract "Inherited bleeding disorders (IBDs) in women are more common than previously suspected. Women with IBDs are at risk of heavy bleeding from haemostatic challenges such as menstruation and childbirth. These common haemostatic challenges can cause symptoms even in mildly affected women thus increasing the clinical prevalence of IBDs in women compared to men. von Willebrand disease (VWD) is the most common IBD. This has a reported prevalence in the general population of 0.8-1.3%. It is an autosomal disorder resulting from defects in von Willebrand factor (VWF) a protein necessary for haemostasis and an integral part of platelet adhesion and thrombus formation. VWF also acts as a carrier for factor VIII (an essential clotting factor) in the circulation. (excerpt)" @default.
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• W2016979253 date "2008-04-01" @default.
• W2016979253 modified "2023-09-25" @default.
• W2016979253 title "Gynaecological problems and choices for contraception in women with inherited bleeding disorders" @default.
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• W2016979253 doi "https://doi.org/10.1783/jfp.34.2.93" @default.
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