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• W2016988911 abstract "Ecdysteroids, molting hormones of insects, can exert several mild, non-hormonal bioactivities in mammals, including humans. In a previous study, we have found a significant effect of certain derivatives on the ABCB1 transporter mediated multi-drug resistance of a transfected murine leukemia cell line. In this paper, we present a structure-activity relationship study focused on the apolar dioxolane derivatives of 20-hydroxyecdysone. Semi-synthesis and bioactivity of a total of 32 ecdysteroids, including 20 new compounds, is presented, supplemented with their complete 1H- and 13C-NMR signal assignment." @default.
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• W2016988911 date "2013-12-10" @default.
• W2016988911 modified "2023-10-14" @default.
• W2016988911 title "Synthesis and Structure-Activity Relationships of Novel Ecdysteroid Dioxolanes as MDR Modulators in Cancer" @default.
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• W2016988911 doi "https://doi.org/10.3390/molecules181215255" @default.
• W2016988911 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6269874" @default.
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